The Yankees became the first team in major league history to open a game with three consecutive home runs more than once in a season.
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| St. Louis Cardinals vs New York Mets | |
| Type: Total - Status: OPEN | |
| Over - 1H | -105 |
| Under - 1H | -125 |
| Pittsburgh Pirates vs San Diego Padres | |
| Type: Total - Status: OPEN | |
| Over - 1H | -115 |
| Under - 1H | -115 |
| Boston Red Sox vs Minnesota Twins | |
| Type: Runline - Status: OPEN | |
| Minnesota Twins | -110 |
| Boston Red Sox | -110 |
| New York Yankees vs Tampa Bay Rays | |
| Type: Moneyline - Status: OPEN | |
| Tampa Bay Rays - 1I | +125 |
| New York Yankees - 1I | -165 |
| Baltimore Orioles vs Kansas City Royals | |
| Type: Moneyline - Status: OPEN | |
| Kansas City Royals - 1I | +105 |
| Baltimore Orioles - 1I | -135 |
| Toronto Blue Jays vs Cleveland Guardians | |
| Type: Runline - Status: OPEN | |
| Cleveland Guardians | -220 |
| Toronto Blue Jays | +180 |
| Miami Marlins vs Athletics | |
| Type: Runline - Status: OPEN | |
| Miami Marlins - 1H | -135 |
| Athletics - 1H | +105 |
| Philadelphia Phillies vs Arizona Diamondbacks | |
| Type: Total - Status: OPEN | |
| Over - 1H | -130 |
| Under - 1H | +100 |
| Milwaukee Brewers vs Chicago Cubs | |
| Type: Moneyline - Status: OPEN | |
| Milwaukee Brewers - 1I | -120 |
| Chicago Cubs - 1I | -110 |
| Chicago White Sox vs Houston Astros | |
| Type: Runline - Status: OPEN | |
| Houston Astros | -125 |
| Chicago White Sox | +105 |
| Texas Rangers vs Seattle Mariners | |
| Type: Total - Status: OPEN | |
| Under - 1H | -120 |
| Over - 1H | -110 |
| San Francisco Giants vs Colorado Rockies | |
| Type: Total - Status: OPEN | |
| Over - 1H | -125 |
| Under - 1H | -105 |
| Los Angeles Angels vs Detroit Tigers | |
| Type: Moneyline - Status: OPEN | |
| Los Angeles Angels - 1I | +105 |
| Detroit Tigers - 1I | -135 |
| Cincinnati Reds vs Washington Nationals | |
| Type: Moneyline - Status: OPEN | |
| Washington Nationals - 1I | +100 |
| Cincinnati Reds - 1I | -130 |
| St. Louis Cardinals vs New York Mets | |
| Type: Runline - Status: OPEN | |
| St. Louis Cardinals - 1H | -135 |
| New York Mets - 1H | +105 |
| Atlanta Braves vs Los Angeles Dodgers | |
| Type: Total - Status: OPEN | |
| Over - 1H | -115 |
| Under - 1H | -115 |
