The Astros, Yankees and Dodgers have buried the competition, and the Braves, Twins and Cardinals currently lead their respective divisions. Which of these playoff contenders has the edge in the Fall Classic?
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| Conspiradores de Queretaro vs Bravos de Leon | |
| Type: Total - Status: OPEN | |
| Under | -120 |
| Over | -120 |
| Generales De Durango vs Saraperos de Saltillo | |
| Type: Moneyline - Status: OPEN | |
| Saraperos de Saltillo | -120 |
| Generales De Durango | -120 |
| Houston Astros vs San Diego Padres | |
| Type: Total - Status: OPEN | |
| Over - 1H | -105 |
| Under - 1H | -125 |
| Acereros de Monclova vs Tecolotes de los Dos Laredos | |
| Type: Total - Status: OPEN | |
| Under | -120 |
| Over | -120 |
| Piratas de Campeche vs Tigres de Quintana Roo | |
| Type: Total - Status: OPEN | |
| Under | -110 |
| Over | -130 |
| El Aguila de Veracruz vs Pericos de Puebla | |
| Type: Moneyline - Status: OPEN | |
| El Aguila de Veracruz | -155 |
| Pericos de Puebla | +110 |
| Olmecas de Tabasco vs Guerreros de Oaxaca | |
| Type: Total - Status: OPEN | |
| Under | -120 |
| Over | -120 |
| Toros de Tijuana vs Rieleros de Aguascalientes | |
| Type: Runline - Status: OPEN | |
| Toros de Tijuana | +105 |
| Rieleros de Aguascalientes | -150 |
| Colorado Rockies vs Washington Nationals | |
| Type: Total - Status: OPEN | |
| Under - 1I | -215 |
| Over - 1I | +160 |
| Algodoneros del Unión Laguna vs Dorados de Chihuahua | |
| Type: Runline - Status: OPEN | |
| Algodoneros del Unión Laguna | -135 |
| Dorados de Chihuahua | -105 |
| Boston Red Sox vs Chicago White Sox | |
| Type: Total - Status: OPEN | |
| Over - 1H | +100 |
| Under - 1H | -130 |
| Cleveland Guardians vs New York Yankees | |
| Type: Moneyline - Status: OPEN | |
| New York Yankees - 1I | -110 |
| Cleveland Guardians - 1I | -120 |
| Miami Marlins vs Cincinnati Reds | |
| Type: Moneyline - Status: OPEN | |
| Miami Marlins - 1I | -115 |
| Cincinnati Reds - 1I | -115 |
| New York Mets vs Philadelphia Phillies | |
| Type: Total - Status: SUSPENDED | |
| Over - 1I | |
| Under - 1I | |
| Atlanta Braves vs St. Louis Cardinals | |
| Type: Total - Status: OPEN | |
| Over | +100 |
| Under | -120 |
| San Francisco Giants vs Milwaukee Brewers | |
| Type: Runline - Status: OPEN | |
| San Francisco Giants - 1H | -110 |
| Milwaukee Brewers - 1H | -120 |
