The White Sox tied the post-1900 MLB record for losses Sunday against the Padres, matching the 1962 expansion Mets with 120 defeats.
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| Washington Nationals vs St. Louis Cardinals | |
| Type: Runline - Status: OPEN | |
| St. Louis Cardinals - 1H | -105 |
| Washington Nationals - 1H | -125 |
| Pittsburgh Pirates vs Atlanta Braves | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -105 |
| Detroit Tigers vs Texas Rangers | |
| Type: Moneyline - Status: OPEN | |
| Detroit Tigers - 1H | -110 |
| Texas Rangers - 1H | -120 |
| Tampa Bay Rays vs Milwaukee Brewers | |
| Type: Moneyline - Status: OPEN | |
| Tampa Bay Rays - 1H | -150 |
| Milwaukee Brewers - 1H | +115 |
| Texas (#1) vs Florida | |
| Type: Moneyline - Status: OPEN | |
| Texas (#1) | -145 |
| Florida | +110 |
| Baylor vs Oklahoma State | |
| Type: Total - Status: OPEN | |
| Under | -130 |
| Over | +100 |
| Kansas State vs West Virginia (#12) | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -115 |
| TCU vs Cincinnati | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -115 |
| Texas Tech vs Central Florida | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -115 |
| Texas A&M vs Missouri | |
| Type: Runline - Status: OPEN | |
| Texas A&M | -115 |
| Missouri | -115 |
| Arkansas State vs Troy (#19) | |
| Type: Total - Status: OPEN | |
| Under | +100 |
| Over | -130 |
| Southern Mississippi (#21) vs UL Lafayette | |
| Type: Runline - Status: OPEN | |
| UL Lafayette | +100 |
| Southern Mississippi (#21) | -130 |
| Rutgers vs Penn State | |
| Type: Moneyline - Status: OPEN | |
| Rutgers | -110 |
| Penn State | -120 |
| Dallas Baptist vs Kennesaw State | |
| Type: Runline - Status: OPEN | |
| Dallas Baptist | -115 |
| Kennesaw State | -115 |
| Memphis Tigers vs Tulane | |
| Type: Moneyline - Status: OPEN | |
| Memphis Tigers | +140 |
| Tulane | -185 |
| Chicago White Sox vs Miami Marlins | |
| Type: Moneyline - Status: OPEN | |
| Miami Marlins | -136 |
| Chicago White Sox | +114 |
| Kansas City Royals vs Boston Red Sox | |
| Type: Moneyline - Status: OPEN | |
| Boston Red Sox | +109 |
| Kansas City Royals | -131 |
| Houston Astros vs Cincinnati Reds | |
| Type: Runline - Status: OPEN | |
| Houston Astros - 1H | -105 |
| Cincinnati Reds - 1H | -125 |
| Minnesota Twins vs San Francisco Giants | |
| Type: Moneyline - Status: OPEN | |
| Minnesota Twins - 1I | -150 |
| San Francisco Giants - 1I | +115 |
| Arizona Wildcats vs Utah | |
| Type: Moneyline - Status: OPEN | |
| Arizona Wildcats | -300 |
| Utah | +220 |
| Tennessee (#15) vs Vanderbilt (#11) | |
| Type: Runline - Status: OPEN | |
| Tennessee (#15) | -115 |
| Vanderbilt (#11) | -115 |
| Washington State vs UNLV | |
| Type: Runline - Status: OPEN | |
| Washington State | -110 |
| UNLV | -120 |
| Oregon (#5) vs Washington | |
| Type: Runline - Status: OPEN | |
| Oregon (#5) | -120 |
| Washington | -110 |
| Nashville Sounds vs Norfolk Tides | |
| Type: Runline - Status: OPEN | |
| Nashville Sounds | +135 |
| Norfolk Tides | -180 |
| Oklahoma City Dodgers vs Albuquerque Isotopes | |
| Type: Total - Status: OPEN | |
| Under | -105 |
| Over | -125 |
| Colorado Rockies vs San Diego Padres | |
| Type: Moneyline - Status: OPEN | |
| San Diego Padres - 1I | -215 |
| Colorado Rockies - 1I | +160 |
| LSU (#3) vs Arkansas (#7) | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -115 |
| Arizona State vs Houston | |
| Type: Moneyline - Status: OPEN | |
| Arizona State | -275 |
| Houston | +200 |
| California vs Florida State (#2) | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -115 |
| CS Fullerton vs Hawaii | |
| Type: Runline - Status: OPEN | |
| CS Fullerton | +120 |
| Hawaii | -160 |
| Indiana vs Purdue | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -115 |
| USC (#25) vs Michigan State | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -115 |
| CSU Bakersfield vs UC Irvine (#13) | |
| Type: Runline - Status: OPEN | |
| CSU Bakersfield | +180 |
| UC Irvine (#13) | -245 |
| Stanford vs Grand Canyon | |
| Type: Runline - Status: OPEN | |
| Stanford | -110 |
| Grand Canyon | -120 |
| Athletics vs New York Yankees | |
| Type: Moneyline - Status: OPEN | |
| New York Yankees - 1H | -135 |
| Athletics - 1H | +105 |
| Los Angeles Angels vs Baltimore Orioles | |
| Type: Moneyline - Status: OPEN | |
| Baltimore Orioles | -145 |
| Los Angeles Angels | +122 |
| Arizona Diamondbacks vs Los Angeles Dodgers | |
| Type: Moneyline - Status: OPEN | |
| Arizona Diamondbacks | -112 |
| Los Angeles Dodgers | -108 |
| Seattle Mariners vs Toronto Blue Jays | |
| Type: Total - Status: OPEN | |
| Over | +100 |
| Under | -120 |
| Cleveland Guardians vs Philadelphia Phillies | |
| Type: Moneyline - Status: OPEN | |
| Cleveland Guardians - 1I | +105 |
| Philadelphia Phillies - 1I | -135 |
