The Twins will open their AL Central title defense without closer Jhoan Duran, who has a moderate oblique strain.
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| Murray State vs Mississippi (#10) | |
| Type: Total - Status: OPEN | |
| Under | -110 |
| Over | -120 |
| Acereros de Monclova vs Generales De Durango | |
| Type: Runline - Status: OPEN | |
| Acereros de Monclova | -120 |
| Generales De Durango | -120 |
| Bravos de Leon vs Leones de Yucatan | |
| Type: Moneyline - Status: OPEN | |
| Bravos de Leon | +115 |
| Leones de Yucatan | -160 |
| Rieleros de Aguascalientes vs Sultanes de Monterrey | |
| Type: Moneyline - Status: OPEN | |
| Rieleros de Aguascalientes | +145 |
| Sultanes de Monterrey | -205 |
| UTSA vs Texas (#2) | |
| Type: Runline - Status: OPEN | |
| UTSA | +100 |
| Texas (#2) | -130 |
| Albuquerque Isotopes vs Sugar Land Space Cowboys | |
| Type: Moneyline - Status: OPEN | |
| Albuquerque Isotopes | +105 |
| Sugar Land Space Cowboys | -135 |
| NC State vs Auburn (#4) | |
| Type: Runline - Status: OPEN | |
| NC State | -115 |
| Auburn (#4) | -115 |
| Wright State vs Louisville | |
| Type: Runline - Status: OPEN | |
| Wright State | -115 |
| Louisville | -115 |
| Arkansas Little Rock vs LSU (#6) | |
| Type: Runline - Status: OPEN | |
| Arkansas Little Rock | -115 |
| LSU (#6) | -115 |
| Arkansas (#3) vs Creighton | |
| Type: Runline - Status: OPEN | |
| Arkansas (#3) | -115 |
| Creighton | -115 |
| Tecolotes de los Dos Laredos vs Algodoneros del Unión Laguna | |
| Type: Total - Status: OPEN | |
| Under | -120 |
| Over | -120 |
| Miami Marlins vs Colorado Rockies | |
| Type: Moneyline - Status: OPEN | |
| Miami Marlins - 1H | -200 |
| Colorado Rockies - 1H | +150 |
| Cincinnati Reds vs Milwaukee Brewers | |
| Type: Runline - Status: SUSPENDED | |
| Cincinnati Reds - 1I | |
| Milwaukee Brewers - 1I | |
| Boston Red Sox vs Los Angeles Angels | |
| Type: Moneyline - Status: OPEN | |
| Boston Red Sox - 1H | -150 |
| Los Angeles Angels - 1H | +115 |
| Chicago White Sox vs Detroit Tigers | |
| Type: Moneyline - Status: OPEN | |
| Chicago White Sox - 1I | +105 |
| Detroit Tigers - 1I | -135 |