The Indians keep waiting for their lineup to wake from its April slumber. On Wednesday night, there were signs of life in the form of three home runs, providing just enough support for another strong showing from Trevor Bauer. In a 4-1 victory at Progressive Field, Francisco Lindor, Edwin Encarnacion and Brandon Guyer delivered solo shots off Cubs lefty Jon Lester. With the win, Cleveland and Chicago split the quick two-game series between the 2016 World Series combatants.
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| Cleveland Guardians vs Milwaukee Brewers | |
| Type: Runline - Status: OPEN | |
| Milwaukee Brewers - 1H | -130 |
| Cleveland Guardians - 1H | +100 |
| Baltimore Orioles vs Minnesota Twins | |
| Type: Runline - Status: OPEN | |
| Minnesota Twins | -185 |
| Baltimore Orioles | +160 |
| Detroit Tigers vs Boston Red Sox | |
| Type: Runline - Status: OPEN | |
| Boston Red Sox | +150 |
| Detroit Tigers | -175 |
| Cincinnati Reds vs Chicago White Sox | |
| Type: Total - Status: SUSPENDED | |
| Under - 1I | |
| Over - 1I | |
| Philadelphia Phillies vs St. Louis Cardinals | |
| Type: Moneyline - Status: OPEN | |
| Philadelphia Phillies | -158 |
| St. Louis Cardinals | +132 |
| Toronto Blue Jays vs Tampa Bay Rays | |
| Type: Runline - Status: OPEN | |
| Tampa Bay Rays - 1H | -135 |
| Toronto Blue Jays - 1H | +105 |
| New York Mets vs Pittsburgh Pirates | |
| Type: Total - Status: OPEN | |
| Over - 1H | +100 |
| Under - 1H | -130 |
| Atlanta Braves vs Washington Nationals | |
| Type: Total - Status: OPEN | |
| Over - 1H | +100 |
| Under - 1H | -130 |
| Chicago Cubs vs Miami Marlins | |
| Type: Runline - Status: OPEN | |
| Chicago Cubs | -120 |
| Miami Marlins | +100 |
| Texas Rangers vs Colorado Rockies | |
| Type: Runline - Status: OPEN | |
| Texas Rangers | -110 |
| Colorado Rockies | -110 |
| Houston Astros vs Kansas City Royals | |
| Type: Moneyline - Status: OPEN | |
| Kansas City Royals - 1H | +115 |
| Houston Astros - 1H | -150 |
| Seattle Mariners vs New York Yankees | |
| Type: Moneyline - Status: OPEN | |
| New York Yankees - 1I | -115 |
| Seattle Mariners - 1I | -115 |
| San Diego Padres vs Los Angeles Angels | |
| Type: Moneyline - Status: OPEN | |
| San Diego Padres - 1I | -170 |
| Los Angeles Angels - 1I | +130 |
| San Francisco Giants vs Arizona Diamondbacks | |
| Type: Runline - Status: OPEN | |
| Arizona Diamondbacks | +155 |
| San Francisco Giants | -180 |
| Los Angeles Dodgers vs Athletics | |
| Type: Moneyline - Status: OPEN | |
| Athletics | +167 |
| Los Angeles Dodgers | -204 |
