Puerto Rico natives Jose Berrios and Eddie Rosario thrilled their home crowd in the longest Major League game ever held at Hiram Bithorn Stadium, a 2-1 win for the Twins in 16 innings. Berrios dueled Indians starter Carlos Carrasco over seven scoreless innings, long before Edwin Encarnacion and Miguel Sano each swatted home runs in the 14th frame of the 5-hour, 13-minute Puerto Rico Series finale.
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| Type: Runline - Status: OPEN | |
| Cleveland Guardians - 1H | -125 |
| Milwaukee Brewers - 1H | -105 |
| Detroit Tigers vs Boston Red Sox | |
| Type: Runline - Status: SUSPENDED | |
| Boston Red Sox - 1I | |
| Detroit Tigers - 1I | |
| Philadelphia Phillies vs St. Louis Cardinals | |
| Type: Moneyline - Status: OPEN | |
| St. Louis Cardinals - 1I | +120 |
| Philadelphia Phillies - 1I | -160 |
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| Type: Runline - Status: OPEN | |
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| Pittsburgh Pirates | -195 |
| Atlanta Braves vs Washington Nationals | |
| Type: Runline - Status: OPEN | |
| Atlanta Braves | +115 |
| Washington Nationals | -135 |
| Chicago Cubs vs Miami Marlins | |
| Type: Total - Status: OPEN | |
| Over | -110 |
| Under | -110 |
| Texas Rangers vs Colorado Rockies | |
| Type: Total - Status: OPEN | |
| Over - 1H | -105 |
| Under - 1H | -125 |
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