Tarik Skubal kept up his stellar season with a sensational playoff debut and the Tigers got to Framber Valdez early in a 3-1 win over the Astros, their first in the playoffs since 2013.
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| San Francisco vs Utah Valley | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -115 |
| Indianapolis Indians vs Louisville Bats | |
| Type: Total - Status: OPEN | |
| Under | -105 |
| Over | -125 |
| Philadelphia Phillies vs St. Louis Cardinals | |
| Type: Total - Status: OPEN | |
| Under - 1I | -340 |
| Over - 1I | +240 |
| Norfolk Tides vs Jacksonville Jumbo Shrimp | |
| Type: Moneyline - Status: OPEN | |
| Norfolk Tides | +115 |
| Jacksonville Jumbo Shrimp | -150 |
| Detroit Tigers vs Boston Red Sox | |
| Type: Total - Status: OPEN | |
| Under | -110 |
| Over | -110 |
| Gwinnett Stripers vs Charlotte Knights | |
| Type: Total - Status: OPEN | |
| Under | -125 |
| Over | -105 |
| Toronto Blue Jays vs Tampa Bay Rays | |
| Type: Total - Status: OPEN | |
| Over - 1H | -110 |
| Under - 1H | -120 |
| New York Mets vs Pittsburgh Pirates | |
| Type: Moneyline - Status: OPEN | |
| Pittsburgh Pirates - 1H | +175 |
| New York Mets - 1H | -240 |
| Cincinnati Reds vs Chicago White Sox | |
| Type: Moneyline - Status: OPEN | |
| Cincinnati Reds | -196 |
| Chicago White Sox | +161 |
| Atlanta Braves vs Washington Nationals | |
| Type: Moneyline - Status: OPEN | |
| Atlanta Braves - 1I | -160 |
| Washington Nationals - 1I | +120 |
| Chicago Cubs vs Miami Marlins | |
| Type: Runline - Status: OPEN | |
| Chicago Cubs - 1H | -105 |
| Miami Marlins - 1H | -125 |
| Texas Rangers vs Colorado Rockies | |
| Type: Total - Status: OPEN | |
| Over | -105 |
| Under | -115 |
| Houston Astros vs Kansas City Royals | |
| Type: Moneyline - Status: OPEN | |
| Kansas City Royals | +105 |
| Houston Astros | -125 |
| Conspiradores de Queretaro vs Tigres de Quintana Roo | |
| Type: Moneyline - Status: OPEN | |
| Conspiradores de Queretaro | -140 |
| Tigres de Quintana Roo | +100 |
| Pericos de Puebla vs Leones de Yucatan | |
| Type: Moneyline - Status: OPEN | |
| Pericos de Puebla | -185 |
| Leones de Yucatan | +130 |
| Sultanes de Monterrey vs Dorados de Chihuahua | |
| Type: Runline - Status: OPEN | |
| Sultanes de Monterrey | +100 |
| Dorados de Chihuahua | -140 |
| Piratas de Campeche vs El Aguila de Veracruz | |
| Type: Total - Status: OPEN | |
| Under | -135 |
| Over | -105 |
| Algodoneros del Unión Laguna vs Rieleros de Aguascalientes | |
| Type: Total - Status: OPEN | |
| Under | -120 |
| Over | -120 |
| Bravos de Leon vs Guerreros de Oaxaca | |
| Type: Total - Status: OPEN | |
| Under | -130 |
| Over | -110 |
| Saraperos de Saltillo vs Tecolotes de los Dos Laredos | |
| Type: Total - Status: OPEN | |
| Under | -120 |
| Over | -120 |
| Generales De Durango vs Charros de Jalisco | |
| Type: Total - Status: OPEN | |
| Under | -105 |
| Over | -135 |
| San Diego Padres vs Los Angeles Angels | |
| Type: Total - Status: OPEN | |
| Over - 1I | +210 |
| Under - 1I | -290 |
| Acereros de Monclova vs Toros de Tijuana | |
| Type: Runline - Status: OPEN | |
| Acereros de Monclova | -170 |
| Toros de Tijuana | +120 |
| Los Angeles Dodgers vs Athletics | |
| Type: Total - Status: OPEN | |
| Under | +100 |
| Over | -120 |
| Hokkaido Nippon-Ham Fighters vs Orix Buffaloes | |
| Type: Moneyline - Status: OPEN | |
| Hokkaido Nippon-Ham Fighters | -115 |
| Orix Buffaloes | -115 |
| Fukuoka SoftBank Hawks vs Saitama Seibu Lions | |
| Type: Runline - Status: OPEN | |
| Fukuoka SoftBank Hawks | +155 |
| Saitama Seibu Lions | -205 |
| Tohoku Rakuten Golden Eagles vs Chiba Lotte Marines | |
| Type: Runline - Status: OPEN | |
| Tohoku Rakuten Golden Eagles | +185 |
| Chiba Lotte Marines | -250 |
| Hiroshima Toyo Carp vs Yomiuri Giants | |
| Type: Moneyline - Status: OPEN | |
| Hiroshima Toyo Carp | +120 |
| Yomiuri Giants | -155 |
| Yokohama DeNa BayStars vs Hanshin Tigers | |
| Type: Total - Status: OPEN | |
| Under | -105 |
| Over | -125 |
| Hanwha Eagles vs Doosan Bears | |
| Type: Moneyline - Status: OPEN | |
| Hanwha Eagles | -125 |
| Doosan Bears | -105 |
| Kia Tigers vs Lotte Giants | |
| Type: Moneyline - Status: OPEN | |
| Kia Tigers | -190 |
| Lotte Giants | +145 |
| LG Twins vs Kiwoom Heroes | |
| Type: Moneyline - Status: OPEN | |
| LG Twins | -325 |
| Kiwoom Heroes | +230 |
| Samsung Lions vs KT Wiz | |
| Type: Total - Status: OPEN | |
| Under | -105 |
| Over | -125 |
| SSG Landers vs NC Dinos | |
| Type: Runline - Status: OPEN | |
| SSG Landers | +145 |
| NC Dinos | -190 |
| Rakuten Monkeys vs Uni-Lions | |
| Type: Runline - Status: OPEN | |
| Rakuten Monkeys | -150 |
| Uni-Lions | +115 |
