Will the ball keep flying out of the park? Will a group of superteams dominate again? We examine key topics to watch as Opening Day nears.
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| North Carolina (#5) vs Arizona | |
| Type: Runline - Status: OPEN | |
| North Carolina (#5) | -120 |
| Arizona | -110 |
| Tampa Bay Rays vs Miami Marlins | |
| Type: Moneyline - Status: OPEN | |
| Tampa Bay Rays - 1H | -130 |
| Miami Marlins - 1H | +100 |
| Louisville vs Miami Florida | |
| Type: Total - Status: OPEN | |
| Under | -110 |
| Over | -120 |
| Oregon State (#8) vs Florida State (#9) | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -115 |
| Pittsburgh Pirates vs Philadelphia Phillies | |
| Type: Runline - Status: OPEN | |
| Pittsburgh Pirates | -140 |
| Philadelphia Phillies | +120 |
| Washington Nationals vs Texas Rangers | |
| Type: Total - Status: OPEN | |
| Under | -110 |
| Over | -110 |
| New York Yankees vs Boston Red Sox | |
| Type: Total - Status: OPEN | |
| Under - 1H | -130 |
| Over - 1H | +100 |
| Detroit Tigers vs Chicago Cubs | |
| Type: Runline - Status: OPEN | |
| Detroit Tigers - 1H | -125 |
| Chicago Cubs - 1H | -105 |
| Cincinnati Reds vs Arizona Diamondbacks | |
| Type: Moneyline - Status: OPEN | |
| Cincinnati Reds | -103 |
| Arizona Diamondbacks | -117 |
| Cleveland Guardians vs Houston Astros | |
| Type: Total - Status: OPEN | |
| Under | -120 |
| Over | +100 |
| Chicago White Sox vs Kansas City Royals | |
| Type: Total - Status: OPEN | |
| Under | -105 |
| Over | -115 |
| Beijing Tiger vs Tianjin Lion | |
| Type: Runline - Status: OPEN | |
| Beijing Tiger | -115 |
| Tianjin Lion | -115 |
| Milwaukee Brewers vs San Diego Padres | |
| Type: Moneyline - Status: OPEN | |
| Milwaukee Brewers - 1I | -145 |
| San Diego Padres - 1I | +110 |
| Minnesota Twins vs Toronto Blue Jays | |
| Type: Moneyline - Status: OPEN | |
| Minnesota Twins - 1H | -135 |
| Toronto Blue Jays - 1H | +105 |
| St. Louis Cardinals vs Los Angeles Dodgers | |
| Type: Moneyline - Status: OPEN | |
| St. Louis Cardinals - 1H | -150 |
| Los Angeles Dodgers - 1H | +115 |
| Colorado Rockies vs New York Mets | |
| Type: Runline - Status: OPEN | |
| Colorado Rockies - 1H | +110 |
| New York Mets - 1H | -145 |
| Auburn (#4) vs Coastal Carolina (#13) | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -115 |
| Los Angeles Angels vs Seattle Mariners | |
| Type: Runline - Status: OPEN | |
| Los Angeles Angels - 1H | -125 |
| Seattle Mariners - 1H | -105 |
| Athletics vs Baltimore Orioles | |
| Type: Moneyline - Status: OPEN | |
| Athletics - 1H | +100 |
| Baltimore Orioles - 1H | -130 |
| San Francisco Giants vs Atlanta Braves | |
| Type: Total - Status: OPEN | |
| Under | -110 |
| Over | -110 |
| Home Total Runs vs Away Total Runs | |
| Type: Runline - Status: SUSPENDED | |
| Home Total Runs | |
| Away Total Runs | |
| Chunichi Dragons vs Chiba Lotte Marines | |
| Type: Moneyline - Status: OPEN | |
| Chunichi Dragons | -110 |
| Chiba Lotte Marines | -120 |
| Yomiuri Giants vs Tohoku Rakuten Golden Eagles | |
| Type: Runline - Status: OPEN | |
| Yomiuri Giants | +120 |
| Tohoku Rakuten Golden Eagles | -155 |
| Tokyo Yakult Swallows vs Fukuoka SoftBank Hawks | |
| Type: Runline - Status: OPEN | |
| Tokyo Yakult Swallows | -110 |
| Fukuoka SoftBank Hawks | -120 |
| Hiroshima Toyo Carp vs Saitama Seibu Lions | |
| Type: Runline - Status: OPEN | |
| Hiroshima Toyo Carp | -210 |
| Saitama Seibu Lions | +160 |
| Yokohama DeNa BayStars vs Hokkaido Nippon-Ham Fighters | |
| Type: Runline - Status: OPEN | |
| Yokohama DeNa BayStars | +180 |
| Hokkaido Nippon-Ham Fighters | -240 |
| Kia Tigers vs Hanwha Eagles | |
| Type: Moneyline - Status: OPEN | |
| Kia Tigers | -175 |
| Hanwha Eagles | +135 |
| Kiwoom Heroes vs LG Twins | |
| Type: Runline - Status: OPEN | |
| Kiwoom Heroes | -170 |
| LG Twins | +130 |
| Duke vs Murray State | |
| Type: Runline - Status: OPEN | |
| Duke | +100 |
| Murray State | -130 |
| LSU (#6) vs West Virginia | |
| Type: Moneyline - Status: OPEN | |
| LSU (#6) | -330 |
| West Virginia | +235 |
| Arkansas (#3) vs Tennessee (#14) | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -115 |
| UCLA (#15) vs UTSA | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -115 |
