Jose Ramirez connected for a two-run homer, Shane Bieber dominated Tampa Bay for 7.2 innings and the young Cleveland Guardians played with poise in their postseason debut, beating the Rays 2-1 in the wild-card opener on Friday.
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| Worcester Red Sox vs Rochester Red Wings | |
| Type: Runline - Status: OPEN | |
| Worcester Red Sox | +115 |
| Rochester Red Wings | -150 |
| Charlotte Knights vs Lehigh Valley IronPigs | |
| Type: Runline - Status: OPEN | |
| Charlotte Knights | -115 |
| Lehigh Valley IronPigs | -115 |
| Louisville Bats vs Norfolk Tides | |
| Type: Runline - Status: OPEN | |
| Louisville Bats | +135 |
| Norfolk Tides | -180 |
| Syracuse Mets vs Buffalo Bisons | |
| Type: Moneyline - Status: OPEN | |
| Syracuse Mets | -135 |
| Buffalo Bisons | +105 |
| Miami Marlins vs Colorado Rockies | |
| Type: Total - Status: OPEN | |
| Under - 1I | -340 |
| Over - 1I | +240 |
| Pittsburgh Pirates vs Houston Astros | |
| Type: Total - Status: OPEN | |
| Under - 1I | -460 |
| Over - 1I | +310 |
| Washington Nationals vs Chicago Cubs | |
| Type: Moneyline - Status: OPEN | |
| Washington Nationals - 1H | +105 |
| Chicago Cubs - 1H | -135 |
| New York Yankees vs Cleveland Guardians | |
| Type: Total - Status: OPEN | |
| Under | -110 |
| Over | -110 |
| Jacksonville Jumbo Shrimp vs Durham Bulls | |
| Type: Total - Status: OPEN | |
| Under | -105 |
| Over | -125 |
| Toronto Blue Jays vs Philadelphia Phillies | |
| Type: Moneyline - Status: OPEN | |
| Toronto Blue Jays | +117 |
| Philadelphia Phillies | -140 |
| Boston Red Sox vs Los Angeles Angels | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -105 |
| Cincinnati Reds vs Milwaukee Brewers | |
| Type: Runline - Status: OPEN | |
| Cincinnati Reds - 1H | +100 |
| Milwaukee Brewers - 1H | -130 |
| Atlanta Braves vs Arizona Diamondbacks | |
| Type: Moneyline - Status: OPEN | |
| Atlanta Braves | -168 |
| Arizona Diamondbacks | +140 |
| Tampa Bay Rays vs Texas Rangers | |
| Type: Runline - Status: OPEN | |
| Tampa Bay Rays - 1H | -115 |
| Texas Rangers - 1H | -115 |
| Chicago White Sox vs Detroit Tigers | |
| Type: Moneyline - Status: OPEN | |
| Chicago White Sox - 1H | +100 |
| Detroit Tigers - 1H | -130 |
| St. Louis Cardinals vs Kansas City Royals | |
| Type: Moneyline - Status: OPEN | |
| St. Louis Cardinals - 1I | -145 |
| Kansas City Royals - 1I | +110 |
| Oklahoma City Dodgers vs Reno Aces | |
| Type: Moneyline - Status: OPEN | |
| Oklahoma City Dodgers | -160 |
| Reno Aces | +120 |
| Sugar Land Space Cowboys vs Sacramento River Cats | |
| Type: Moneyline - Status: OPEN | |
| Sugar Land Space Cowboys | -150 |
| Sacramento River Cats | +115 |
| Omaha Storm Chasers vs Iowa Cubs | |
| Type: Moneyline - Status: OPEN | |
| Omaha Storm Chasers | +110 |
| Iowa Cubs | -145 |
| Memphis Redbirds vs Indianapolis Indians | |
| Type: Total - Status: OPEN | |
| Under | -110 |
| Over | -120 |
| St. Paul Saints vs Scranton Wilkes-Barre RailRiders | |
| Type: Runline - Status: OPEN | |
| St. Paul Saints | +130 |
| Scranton Wilkes-Barre RailRiders | -170 |
| Tecolotes de los Dos Laredos vs Rieleros de Aguascalientes | |
| Type: Runline - Status: OPEN | |
| Tecolotes de los Dos Laredos | -115 |
| Rieleros de Aguascalientes | -125 |
| El Paso Chihuahuas vs Albuquerque Isotopes | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -115 |
| El Aguila de Veracruz vs Diablos Rojos del México | |
| Type: Total - Status: OPEN | |
| Under | -120 |
| Over | -120 |
| Guerreros de Oaxaca vs Piratas de Campeche | |
| Type: Moneyline - Status: OPEN | |
| Guerreros de Oaxaca | -240 |
| Piratas de Campeche | +165 |
| Salt Lake Bees vs Round Rock Express | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -115 |
| Leones de Yucatan vs Conspiradores de Queretaro | |
| Type: Total - Status: OPEN | |
| Under | -120 |
| Over | -120 |
| Sultanes de Monterrey vs Saraperos de Saltillo | |
| Type: Runline - Status: OPEN | |
| Sultanes de Monterrey | -115 |
| Saraperos de Saltillo | -125 |
| Olmecas de Tabasco vs Tigres de Quintana Roo | |
| Type: Runline - Status: OPEN | |
| Olmecas de Tabasco | -110 |
| Tigres de Quintana Roo | -130 |
| Generales De Durango vs Dorados de Chihuahua | |
| Type: Moneyline - Status: OPEN | |
| Generales De Durango | -110 |
| Dorados de Chihuahua | -130 |
| Seattle Mariners vs Baltimore Orioles | |
| Type: Total - Status: OPEN | |
| Under | -110 |
| Over | -110 |
| San Francisco Giants vs San Diego Padres | |
| Type: Moneyline - Status: OPEN | |
| San Francisco Giants | -160 |
| San Diego Padres | +134 |
| Acereros de Monclova vs Algodoneros del Unión Laguna | |
| Type: Total - Status: OPEN | |
| Under | -120 |
| Over | -120 |
| Athletics vs Minnesota Twins | |
| Type: Runline - Status: OPEN | |
| Athletics | +105 |
| Minnesota Twins | -125 |
| Toros de Tijuana vs Charros de Jalisco | |
| Type: Moneyline - Status: OPEN | |
| Toros de Tijuana | -205 |
| Charros de Jalisco | +145 |
| Los Angeles Dodgers vs New York Mets | |
| Type: Runline - Status: OPEN | |
| Los Angeles Dodgers | +140 |
| New York Mets | -165 |
| Home Total Runs vs Away Total Runs | |
| Type: Total - Status: OPEN | |
| Under | -120 |
| Over | +100 |
| Hokkaido Nippon-Ham Fighters vs Hanshin Tigers | |
| Type: Total - Status: OPEN | |
| Under | -110 |
| Over | -120 |
| Fukuoka SoftBank Hawks vs Chunichi Dragons | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -115 |
| Chiba Lotte Marines vs Yomiuri Giants | |
| Type: Moneyline - Status: OPEN | |
| Chiba Lotte Marines | +120 |
| Yomiuri Giants | -155 |
| Tohoku Rakuten Golden Eagles vs Yokohama DeNa BayStars | |
| Type: Total - Status: OPEN | |
| Under | -110 |
| Over | -120 |
| Saitama Seibu Lions vs Tokyo Yakult Swallows | |
| Type: Total - Status: OPEN | |
| Under | -125 |
| Over | -105 |
| Orix Buffaloes vs Hiroshima Toyo Carp | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -115 |
| Doosan Bears vs Kia Tigers | |
| Type: Moneyline - Status: OPEN | |
| Doosan Bears | +135 |
| Kia Tigers | -175 |
| Hanwha Eagles vs KT Wiz | |
| Type: Runline - Status: OPEN | |
| Hanwha Eagles | +120 |
| KT Wiz | -155 |
| Lotte Giants vs Kiwoom Heroes | |
| Type: Moneyline - Status: OPEN | |
| Lotte Giants | -275 |
| Kiwoom Heroes | +200 |
| NC Dinos vs LG Twins | |
| Type: Runline - Status: OPEN | |
| NC Dinos | -165 |
| LG Twins | +125 |
| SSG Landers vs Samsung Lions | |
| Type: Runline - Status: OPEN | |
| SSG Landers | -105 |
| Samsung Lions | -125 |
| Wei Chuan Dragons vs Fubon Guardians | |
| Type: Runline - Status: OPEN | |
| Wei Chuan Dragons | -105 |
| Fubon Guardians | -125 |
| Rakuten Monkeys vs CTBC Brothers | |
| Type: Total - Status: OPEN | |
| Under | -120 |
| Over | -110 |
| Uni-Lions vs TSG Hawks | |
| Type: Moneyline - Status: OPEN | |
| Uni-Lions | -155 |
| TSG Hawks | +120 |