The baseball that Jose Ramirez deposited in the basket above the ivy-covered wall in right at Wrigley Field was just the start. The Indians have plenty of bad memories when it comes to the Cubs, but Tuesday night did not stir any flashbacks. Ramirez saw to that in the third inning, when he launched a three-run home run off Cubs righty Tyler Chatwood to ignite a 10-1 rout for the Tribe in its first trip back to the Friendly Confines since the 2016 World Series. There is no rewriting that history, but Cleveland turned in a much more memorable box score this time around.
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| Miami Florida vs Georgia Tech (#14) | |
| Type: Moneyline - Status: OPEN | |
| Miami Florida | +175 |
| Georgia Tech (#14) | -240 |
| Michigan vs Iowa Cubs | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -115 |
| Penn State vs Purdue | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -115 |
| Oklahoma State vs Houston | |
| Type: Moneyline - Status: OPEN | |
| Oklahoma State | -185 |
| Houston | +140 |
| Tennessee (#4) vs Kentucky | |
| Type: Moneyline - Status: OPEN | |
| Tennessee (#4) | -475 |
| Kentucky | +320 |
| Atlanta Braves vs Minnesota Twins | |
| Type: Total - Status: OPEN | |
| Over - 1I | +240 |
| Under - 1I | -340 |
| Boston Red Sox vs Chicago White Sox | |
| Type: Runline - Status: OPEN | |
| Chicago White Sox - 1H | +105 |
| Boston Red Sox - 1H | -135 |
| Baltimore Orioles vs Cincinnati Reds | |
| Type: Moneyline - Status: OPEN | |
| Baltimore Orioles | -199 |
| Cincinnati Reds | +164 |
| Pittsburgh Pirates vs Cleveland Guardians | |
| Type: Moneyline - Status: OPEN | |
| Pittsburgh Pirates - 1H | -135 |
| Cleveland Guardians - 1H | +105 |
| Philadelphia Phillies vs Miami Marlins | |
| Type: Moneyline - Status: OPEN | |
| Miami Marlins | +250 |
| Philadelphia Phillies | -310 |
| Toronto Blue Jays vs Seattle Mariners | |
| Type: Moneyline - Status: OPEN | |
| Seattle Mariners | -114 |
| Toronto Blue Jays | -106 |
| Detroit Tigers vs Kansas City Royals | |
| Type: Total - Status: OPEN | |
| Under - 1I | -450 |
| Over - 1I | +300 |
| New York Mets vs St. Louis Cardinals | |
| Type: Total - Status: OPEN | |
| Under - 1I | -420 |
| Over - 1I | +285 |
| Tampa Bay Rays vs New York Yankees | |
| Type: Moneyline - Status: OPEN | |
| Tampa Bay Rays | +146 |
| New York Yankees | -178 |
| Las Tunas vs Industriales | |
| Type: Runline - Status: OPEN | |
| Las Tunas | +120 |
| Industriales | -170 |
| Milwaukee Brewers vs Athletics | |
| Type: Total - Status: OPEN | |
| Over - 1I | +240 |
| Under - 1I | -340 |
| Chicago Cubs vs Arizona Diamondbacks | |
| Type: Moneyline - Status: OPEN | |
| Arizona Diamondbacks - 1H | +105 |
| Chicago Cubs - 1H | -135 |
| Texas Rangers vs Los Angeles Dodgers | |
| Type: Total - Status: OPEN | |
| Over - 1H | -125 |
| Under - 1H | -105 |
| Colorado Rockies vs Washington Nationals | |
| Type: Runline - Status: SUSPENDED | |
| Colorado Rockies | -150 |
| Washington Nationals | +130 |
| Los Angeles Angels vs San Francisco Giants | |
| Type: Moneyline - Status: OPEN | |
| San Francisco Giants | -107 |
| Los Angeles Angels | -113 |
| Houston Astros vs San Diego Padres | |
| Type: Total - Status: OPEN | |
| Over - 1H | -130 |
| Under - 1H | +100 |
| Colorado Rockies vs Washington Nationals | |
| Type: Total - Status: OPEN | |
| Under - 1I | -215 |
| Over - 1I | +160 |