General manager Dave Littlefield was fired Friday by the Pittsburgh Pirates after six-plus seasons in which the team showed little progress on the field or in its farm system. Director of player development Brian Graham will serve as the interim general manager until Littlefield’s replacement is found.
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| Washington Nationals vs St. Louis Cardinals | |
| Type: Runline - Status: OPEN | |
| St. Louis Cardinals - 1H | -110 |
| Washington Nationals - 1H | -120 |
| Pittsburgh Pirates vs Atlanta Braves | |
| Type: Total - Status: OPEN | |
| Under | -105 |
| Over | -115 |
| New York Mets vs Chicago Cubs | |
| Type: Moneyline - Status: OPEN | |
| Chicago Cubs | +119 |
| New York Mets | -142 |
| Detroit Tigers vs Texas Rangers | |
| Type: Moneyline - Status: OPEN | |
| Detroit Tigers - 1H | -110 |
| Texas Rangers - 1H | -120 |
| Tampa Bay Rays vs Milwaukee Brewers | |
| Type: Moneyline - Status: OPEN | |
| Tampa Bay Rays - 1H | -160 |
| Milwaukee Brewers - 1H | +120 |
| Chicago White Sox vs Miami Marlins | |
| Type: Moneyline - Status: OPEN | |
| Miami Marlins | -142 |
| Chicago White Sox | +119 |
| Kansas City Royals vs Boston Red Sox | |
| Type: Moneyline - Status: OPEN | |
| Boston Red Sox | +109 |
| Kansas City Royals | -131 |
| Houston Astros vs Cincinnati Reds | |
| Type: Runline - Status: OPEN | |
| Houston Astros - 1H | -105 |
| Cincinnati Reds - 1H | -125 |
| Minnesota Twins vs San Francisco Giants | |
| Type: Moneyline - Status: OPEN | |
| Minnesota Twins - 1I | -135 |
| San Francisco Giants - 1I | +105 |
| Colorado Rockies vs San Diego Padres | |
| Type: Moneyline - Status: OPEN | |
| San Diego Padres - 1I | -190 |
| Colorado Rockies - 1I | +145 |
| Athletics vs New York Yankees | |
| Type: Moneyline - Status: OPEN | |
| New York Yankees - 1H | -135 |
| Athletics - 1H | +105 |
| Los Angeles Angels vs Baltimore Orioles | |
| Type: Moneyline - Status: OPEN | |
| Baltimore Orioles | -143 |
| Los Angeles Angels | +120 |
| Arizona Diamondbacks vs Los Angeles Dodgers | |
| Type: Moneyline - Status: OPEN | |
| Arizona Diamondbacks | -111 |
| Los Angeles Dodgers | -109 |
| Seattle Mariners vs Toronto Blue Jays | |
| Type: Total - Status: OPEN | |
| Over | -120 |
| Under | +100 |
| Cleveland Guardians vs Philadelphia Phillies | |
| Type: Moneyline - Status: OPEN | |
| Cleveland Guardians - 1I | +105 |
| Philadelphia Phillies - 1I | -135 |