Big offseason changes — capped by the Bryce Harper signing — need to fix a culture that grew problematic in Gabe Kapler’s first year at the helm.
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| Henan Wolves vs Jiangsu Horse | |
| Type: Runline - Status: OPEN | |
| Henan Wolves | -135 |
| Jiangsu Horse | +105 |
| Fujian vs Tianjin Lion | |
| Type: Total - Status: OPEN | |
| Under | +105 |
| Over | -135 |
| Rieleros de Aguascalientes vs Saraperos de Saltillo | |
| Type: Runline - Status: OPEN | |
| Rieleros de Aguascalientes | -150 |
| Saraperos de Saltillo | +105 |
| Olmecas de Tabasco vs Bravos de Leon | |
| Type: Runline - Status: OPEN | |
| Olmecas de Tabasco | +120 |
| Bravos de Leon | -170 |
| Leones de Yucatan vs El Aguila de Veracruz | |
| Type: Runline - Status: OPEN | |
| Leones de Yucatan | +140 |
| El Aguila de Veracruz | -200 |
| Algodoneros del Unión Laguna vs Toros de Tijuana | |
| Type: Moneyline - Status: OPEN | |
| Algodoneros del Unión Laguna | -125 |
| Toros de Tijuana | -115 |
| Shandong Blue Whale vs Guangdong Leopard | |
| Type: Total - Status: OPEN | |
| Under | -105 |
| Over | -125 |
| Cleveland Guardians vs Milwaukee Brewers | |
| Type: Runline - Status: OPEN | |
| Cleveland Guardians - 1H | -135 |
| Milwaukee Brewers - 1H | +105 |
| Detroit Tigers vs Boston Red Sox | |
| Type: Runline - Status: SUSPENDED | |
| Boston Red Sox - 1I | |
| Detroit Tigers - 1I | |
| New York Mets vs Pittsburgh Pirates | |
| Type: Runline - Status: OPEN | |
| New York Mets | +165 |
| Pittsburgh Pirates | -195 |
| Atlanta Braves vs Washington Nationals | |
| Type: Runline - Status: OPEN | |
| Atlanta Braves | +115 |
| Washington Nationals | -135 |
| Chicago Cubs vs Miami Marlins | |
| Type: Total - Status: SUSPENDED | |
| Over | |
| Under | |
| Texas Rangers vs Colorado Rockies | |
| Type: Total - Status: OPEN | |
| Over - 1H | -110 |
| Under - 1H | -120 |
| San Diego Padres vs Los Angeles Angels | |
| Type: Runline - Status: OPEN | |
| San Diego Padres - 1H | -135 |
| Los Angeles Angels - 1H | +105 |
| San Francisco Giants vs Arizona Diamondbacks | |
| Type: Runline - Status: OPEN | |
| Arizona Diamondbacks | -220 |
| San Francisco Giants | +180 |