David Ortiz will play first base for Boston when the World Series resumes Saturday night, and Kevin Youkilis will be benched as the Red Sox adjust to life without a designated hitter. Mike Lowell will remain at third for the Red Sox, who have a 2-0 Series lead against the Colorado Rockies. Ortiz, bothered by a left knee that will need surgery, worked out at first base Friday.
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| Boston Red Sox vs Chicago White Sox | |
| Type: Total - Status: OPEN | |
| Over - 1H | -130 |
| Under - 1H | +100 |
| Cleveland Guardians vs New York Yankees | |
| Type: Moneyline - Status: OPEN | |
| New York Yankees - 1I | -110 |
| Cleveland Guardians - 1I | -120 |
| Miami Marlins vs Cincinnati Reds | |
| Type: Moneyline - Status: OPEN | |
| Miami Marlins - 1I | -115 |
| Cincinnati Reds - 1I | -115 |
| New York Mets vs Philadelphia Phillies | |
| Type: Total - Status: SUSPENDED | |
| Over - 1I | |
| Under - 1I | |
| Atlanta Braves vs St. Louis Cardinals | |
| Type: Total - Status: OPEN | |
| Over | +100 |
| Under | -120 |
| San Francisco Giants vs Milwaukee Brewers | |
| Type: Runline - Status: OPEN | |
| San Francisco Giants - 1H | -105 |
| Milwaukee Brewers - 1H | -125 |
