With several headliners bowing out, the best Derby showdown would pit mighty mites such as Mookie Betts against super-sized monster mashers.
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| Wei Chuan Dragons vs Uni-Lions | |
| Type: Moneyline - Status: OPEN | |
| Wei Chuan Dragons | -130 |
| Uni-Lions | +100 |
| Fubon Guardians vs CTBC Brothers | |
| Type: Runline - Status: OPEN | |
| Fubon Guardians | -105 |
| CTBC Brothers | -125 |
| Rakuten Monkeys vs TSG Hawks | |
| Type: Moneyline - Status: OPEN | |
| Rakuten Monkeys | -250 |
| TSG Hawks | +185 |
| North Carolina (#5) vs Arizona | |
| Type: Runline - Status: OPEN | |
| North Carolina (#5) | -115 |
| Arizona | -115 |
| Louisville vs Miami Florida | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -115 |
| Oregon State (#8) vs Florida State (#9) | |
| Type: Total - Status: OPEN | |
| Under | -110 |
| Over | -120 |
| Pittsburgh Pirates vs Philadelphia Phillies | |
| Type: Runline - Status: OPEN | |
| Pittsburgh Pirates | -145 |
| Philadelphia Phillies | +125 |
| Washington Nationals vs Texas Rangers | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -105 |
| New York Yankees vs Boston Red Sox | |
| Type: Total - Status: OPEN | |
| Under - 1H | -120 |
| Over - 1H | -110 |
| Cincinnati Reds vs Arizona Diamondbacks | |
| Type: Moneyline - Status: OPEN | |
| Cincinnati Reds | -110 |
| Arizona Diamondbacks | -110 |
| Cleveland Guardians vs Houston Astros | |
| Type: Total - Status: OPEN | |
| Under | +100 |
| Over | -120 |
| Chicago White Sox vs Kansas City Royals | |
| Type: Total - Status: OPEN | |
| Under | -105 |
| Over | -115 |
| Milwaukee Brewers vs San Diego Padres | |
| Type: Moneyline - Status: OPEN | |
| Milwaukee Brewers - 1I | -145 |
| San Diego Padres - 1I | +110 |
| St. Louis Cardinals vs Los Angeles Dodgers | |
| Type: Moneyline - Status: OPEN | |
| St. Louis Cardinals - 1H | -130 |
| Los Angeles Dodgers - 1H | +100 |
| Colorado Rockies vs New York Mets | |
| Type: Runline - Status: OPEN | |
| Colorado Rockies - 1H | +120 |
| New York Mets - 1H | -160 |
| Auburn (#4) vs Coastal Carolina (#13) | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -115 |
| Los Angeles Angels vs Seattle Mariners | |
| Type: Runline - Status: OPEN | |
| Los Angeles Angels - 1H | -125 |
| Seattle Mariners - 1H | -105 |
| San Francisco Giants vs Atlanta Braves | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -105 |
| Duke vs Murray State | |
| Type: Runline - Status: OPEN | |
| Duke | -130 |
| Murray State | +100 |
| LSU (#6) vs West Virginia | |
| Type: Moneyline - Status: OPEN | |
| LSU (#6) | -330 |
| West Virginia | +235 |
| Arkansas (#3) vs Tennessee (#14) | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -115 |
| UCLA (#15) vs UTSA | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -115 |