By reputation, Coors Field is the most unfavorable ballpark for Major League pitchers. The physical toll of maintaining a rest-and-recovery routine at altitude is cited as one major reason why.
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| Washington Nationals vs Cleveland Guardians | |
| Type: Total - Status: OPEN | |
| Under - 1H | -115 |
| Over - 1H | -115 |
| Milwaukee Brewers vs Houston Astros | |
| Type: Total - Status: OPEN | |
| Under | -105 |
| Over | -115 |
| St. Louis Cardinals vs Pittsburgh Pirates | |
| Type: Moneyline - Status: OPEN | |
| Pittsburgh Pirates | +145 |
| St. Louis Cardinals | -177 |
| Ciego de Avila vs Las Tunas | |
| Type: Runline - Status: OPEN | |
| Ciego de Avila | -155 |
| Las Tunas | +110 |
| Chicago Cubs vs San Francisco Giants | |
| Type: Moneyline - Status: OPEN | |
| San Francisco Giants - 1I | +110 |
| Chicago Cubs - 1I | -145 |
| Athletics vs Seattle Mariners | |
| Type: Runline - Status: OPEN | |
| Athletics - 1H | -125 |
| Seattle Mariners - 1H | -105 |
| Arizona Diamondbacks vs New York Mets | |
| Type: Moneyline - Status: OPEN | |
| New York Mets - 1I | -110 |
| Arizona Diamondbacks - 1I | -120 |
| Miami Marlins vs Los Angeles Dodgers | |
| Type: Total - Status: OPEN | |
| Over - 1I | +180 |
| Under - 1I | -245 |
| Boston Red Sox vs Texas Rangers | |
| Type: Total - Status: OPEN | |
| Under - 1I | -275 |
| Over - 1I | +200 |
| New York Yankees vs San Diego Padres | |
| Type: Runline - Status: OPEN | |
| San Diego Padres | -135 |
| New York Yankees | +115 |
| Tampa Bay Rays vs Philadelphia Phillies | |
| Type: Moneyline - Status: OPEN | |
| Tampa Bay Rays | +104 |
| Philadelphia Phillies | -124 |
| Atlanta Braves vs Cincinnati Reds | |
| Type: Moneyline - Status: OPEN | |
| Cincinnati Reds - 1I | -105 |
| Atlanta Braves - 1I | -125 |
| Kansas City Royals vs Chicago White Sox | |
| Type: Moneyline - Status: OPEN | |
| Chicago White Sox - 1H | +160 |
| Kansas City Royals - 1H | -215 |
| Minnesota Twins vs Baltimore Orioles | |
| Type: Total - Status: OPEN | |
| Over - 1I | +180 |
| Under - 1I | -245 |
| Colorado Rockies vs Detroit Tigers | |
| Type: Moneyline - Status: OPEN | |
| Detroit Tigers - 1I | -145 |
| Colorado Rockies - 1I | +110 |
| Los Angeles Angels vs Toronto Blue Jays | |
| Type: Total - Status: OPEN | |
| Over - 1H | -110 |
| Under - 1H | -120 |
