MLB announced plans to suspend players who are caught with foreign substances for 10 days with pay.
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| El Aguila de Veracruz vs Diablos Rojos del México | |
| Type: Total - Status: OPEN | |
| Under | -120 |
| Over | -120 |
| Guerreros de Oaxaca vs Piratas de Campeche | |
| Type: Moneyline - Status: OPEN | |
| Guerreros de Oaxaca | -240 |
| Piratas de Campeche | +165 |
| Salt Lake Bees vs Round Rock Express | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -115 |
| Leones de Yucatan vs Conspiradores de Queretaro | |
| Type: Total - Status: OPEN | |
| Under | -120 |
| Over | -120 |
| Sultanes de Monterrey vs Saraperos de Saltillo | |
| Type: Runline - Status: OPEN | |
| Sultanes de Monterrey | -115 |
| Saraperos de Saltillo | -125 |
| Olmecas de Tabasco vs Tigres de Quintana Roo | |
| Type: Runline - Status: OPEN | |
| Olmecas de Tabasco | -110 |
| Tigres de Quintana Roo | -130 |
| Generales De Durango vs Dorados de Chihuahua | |
| Type: Moneyline - Status: OPEN | |
| Generales De Durango | -110 |
| Dorados de Chihuahua | -130 |
| Seattle Mariners vs Baltimore Orioles | |
| Type: Total - Status: OPEN | |
| Under | -110 |
| Over | -110 |
| San Francisco Giants vs San Diego Padres | |
| Type: Moneyline - Status: OPEN | |
| San Francisco Giants | -160 |
| San Diego Padres | +134 |
| Acereros de Monclova vs Algodoneros del Unión Laguna | |
| Type: Total - Status: OPEN | |
| Under | -120 |
| Over | -120 |
| Athletics vs Minnesota Twins | |
| Type: Runline - Status: OPEN | |
| Athletics | +110 |
| Minnesota Twins | -130 |
| Toros de Tijuana vs Charros de Jalisco | |
| Type: Moneyline - Status: OPEN | |
| Toros de Tijuana | -205 |
| Charros de Jalisco | +145 |
| Los Angeles Dodgers vs New York Mets | |
| Type: Runline - Status: OPEN | |
| Los Angeles Dodgers | +140 |
| New York Mets | -165 |
| Home Total Runs vs Away Total Runs | |
| Type: Runline - Status: SUSPENDED | |
| Home Total Runs | |
| Away Total Runs | |
| Hokkaido Nippon-Ham Fighters vs Hanshin Tigers | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -115 |
| Fukuoka SoftBank Hawks vs Chunichi Dragons | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -115 |
| Chiba Lotte Marines vs Yomiuri Giants | |
| Type: Moneyline - Status: OPEN | |
| Chiba Lotte Marines | +120 |
| Yomiuri Giants | -155 |
| Tohoku Rakuten Golden Eagles vs Yokohama DeNa BayStars | |
| Type: Total - Status: OPEN | |
| Under | -110 |
| Over | -120 |
| Saitama Seibu Lions vs Tokyo Yakult Swallows | |
| Type: Total - Status: OPEN | |
| Under | -125 |
| Over | -105 |
| Orix Buffaloes vs Hiroshima Toyo Carp | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -115 |
| Doosan Bears vs Kia Tigers | |
| Type: Moneyline - Status: OPEN | |
| Doosan Bears | +135 |
| Kia Tigers | -175 |
| Hanwha Eagles vs KT Wiz | |
| Type: Runline - Status: OPEN | |
| Hanwha Eagles | +120 |
| KT Wiz | -155 |
| Lotte Giants vs Kiwoom Heroes | |
| Type: Moneyline - Status: OPEN | |
| Lotte Giants | -275 |
| Kiwoom Heroes | +200 |
| NC Dinos vs LG Twins | |
| Type: Runline - Status: OPEN | |
| NC Dinos | -165 |
| LG Twins | +125 |
| SSG Landers vs Samsung Lions | |
| Type: Runline - Status: OPEN | |
| SSG Landers | -105 |
| Samsung Lions | -125 |
| Wei Chuan Dragons vs Fubon Guardians | |
| Type: Runline - Status: OPEN | |
| Wei Chuan Dragons | -105 |
| Fubon Guardians | -125 |
| Rakuten Monkeys vs CTBC Brothers | |
| Type: Total - Status: OPEN | |
| Under | -120 |
| Over | -110 |
| Uni-Lions vs TSG Hawks | |
| Type: Moneyline - Status: OPEN | |
| Uni-Lions | -155 |
| TSG Hawks | +120 |