It’s not often that the two best teams in the Major Leagues — going by regular season record — meet in the postseason with a league pennant on the line. In 1969, baseball began to expand and split each league into two divisions, creating a need for the American League and National League Championship Series. Since then, the clubs with the two best records in MLB have met in the ALCS or NLCS just eight times.
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| Atlanta Braves vs Washington Nationals | |
| Type: Moneyline - Status: OPEN | |
| Washington Nationals | +171 |
| Atlanta Braves | -211 |
| Baltimore Orioles vs Minnesota Twins | |
| Type: Total - Status: OPEN | |
| Under - 1H | -125 |
| Over - 1H | -105 |
| Cincinnati Reds vs Chicago White Sox | |
| Type: Runline - Status: OPEN | |
| Cincinnati Reds - 1H | -110 |
| Chicago White Sox - 1H | -120 |
| Toronto Blue Jays vs Tampa Bay Rays | |
| Type: Moneyline - Status: OPEN | |
| Tampa Bay Rays - 1I | +120 |
| Toronto Blue Jays - 1I | -160 |
| Texas Rangers vs Houston Astros | |
| Type: Total - Status: OPEN | |
| Over | -120 |
| Under | +100 |
| Los Angeles Dodgers vs Athletics | |
| Type: Runline - Status: OPEN | |
| Athletics | -115 |
| Los Angeles Dodgers | -105 |