Blue Jays outfielder George Springer will start the season on the injured list with a Grade 2 oblique strain.
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| Baltimore Orioles vs St. Louis Cardinals | |
| Type: Runline - Status: OPEN | |
| Baltimore Orioles | +170 |
| St. Louis Cardinals | -200 |
| Indianapolis Indians vs Nashville Sounds | |
| Type: Total - Status: OPEN | |
| Under | -120 |
| Over | -110 |
| Norfolk Tides vs Lehigh Valley IronPigs | |
| Type: Moneyline - Status: OPEN | |
| Norfolk Tides | +140 |
| Lehigh Valley IronPigs | -185 |
| Durham Bulls vs Memphis Redbirds | |
| Type: Moneyline - Status: OPEN | |
| Durham Bulls | -135 |
| Memphis Redbirds | +105 |
| Omaha Storm Chasers vs St. Paul Saints | |
| Type: Runline - Status: OPEN | |
| Omaha Storm Chasers | -170 |
| St. Paul Saints | +130 |
| Kansas City Royals vs Cincinnati Reds | |
| Type: Runline - Status: OPEN | |
| Kansas City Royals | -170 |
| Cincinnati Reds | +145 |
| Texas Rangers vs Toronto Blue Jays | |
| Type: Total - Status: OPEN | |
| Under - 1I | -320 |
| Over - 1I | +230 |
| Chicago Cubs vs Colorado Rockies | |
| Type: Total - Status: OPEN | |
| Under - 1H | -115 |
| Over - 1H | -115 |
| Round Rock Express vs Reno Aces | |
| Type: Runline - Status: SUSPENDED | |
| Round Rock Express | |
| Reno Aces | |
| Tigres de Quintana Roo vs Bravos de Leon | |
| Type: Runline - Status: OPEN | |
| Tigres de Quintana Roo | +165 |
| Bravos de Leon | -240 |
| Albuquerque Isotopes vs Sugar Land Space Cowboys | |
| Type: Total - Status: OPEN | |
| Under | -125 |
| Over | -105 |
| Conspiradores de Queretaro vs El Aguila de Veracruz | |
| Type: Moneyline - Status: OPEN | |
| Conspiradores de Queretaro | -110 |
| El Aguila de Veracruz | -130 |
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| Type: Moneyline - Status: OPEN | |
| Tacoma Rainiers | -125 |
| Salt Lake Bees | -105 |
| Saraperos de Saltillo vs Dorados de Chihuahua | |
| Type: Moneyline - Status: OPEN | |
| Saraperos de Saltillo | -115 |
| Dorados de Chihuahua | -125 |
| Algodoneros del Unión Laguna vs Generales De Durango | |
| Type: Total - Status: OPEN | |
| Under | -120 |
| Over | -120 |
| Sultanes de Monterrey vs Acereros de Monclova | |
| Type: Total - Status: OPEN | |
| Under | -110 |
| Over | -130 |
| Rieleros de Aguascalientes vs Charros de Jalisco | |
| Type: Moneyline - Status: OPEN | |
| Rieleros de Aguascalientes | -105 |
| Charros de Jalisco | -135 |
| Piratas de Campeche vs Leones de Yucatan | |
| Type: Total - Status: OPEN | |
| Under | -120 |
| Over | -120 |
| Olmecas de Tabasco vs Pericos de Puebla | |
| Type: Total - Status: OPEN | |
| Under | -130 |
| Over | -110 |
| Las Vegas Aviators vs Oklahoma City Dodgers | |
| Type: Runline - Status: OPEN | |
| Las Vegas Aviators | +150 |
| Oklahoma City Dodgers | -200 |
| Los Angeles Angels vs New York Yankees | |
| Type: Moneyline - Status: OPEN | |
| Los Angeles Angels | +141 |
| New York Yankees | -170 |
| Seattle Mariners vs Washington Nationals | |
| Type: Total - Status: OPEN | |
| Under - 1I | -295 |
| Over - 1I | +215 |
| Toros de Tijuana vs Tecolotes de los Dos Laredos | |
| Type: Total - Status: OPEN | |
| Under | -120 |
| Over | -120 |
| Saitama Seibu Lions vs Tohoku Rakuten Golden Eagles | |
| Type: Moneyline - Status: OPEN | |
| Saitama Seibu Lions | -130 |
| Tohoku Rakuten Golden Eagles | +100 |
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| Type: Moneyline - Status: OPEN | |
| Hanshin Tigers | -135 |
| Yokohama DeNa BayStars | +105 |
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| Type: Runline - Status: OPEN | |
| Tokyo Yakult Swallows | +145 |
| Chunichi Dragons | -190 |
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| Type: Total - Status: OPEN | |
| Under | -105 |
| Over | -125 |
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| Type: Runline - Status: OPEN | |
| KT Wiz | -165 |
| Doosan Bears | +125 |
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| Type: Total - Status: OPEN | |
| Under | -120 |
| Over | -110 |
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| Type: Moneyline - Status: OPEN | |
| Samsung Lions | +105 |
| Lotte Giants | -135 |
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| Type: Runline - Status: OPEN | |
| SSG Landers | +105 |
| NC Dinos | -135 |
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| Type: Moneyline - Status: OPEN | |
| Georgia (#7) | -1600 |
| Binghamton | +700 |
| East Carolina vs Florida | |
| Type: Moneyline - Status: OPEN | |
| East Carolina | +250 |
| Florida | -360 |
| North Carolina (#5) vs Holy Cross | |
| Type: Moneyline - Status: OPEN | |
| North Carolina (#5) | -1900 |
| Holy Cross | +750 |
| Kentucky vs West Virginia | |
| Type: Moneyline - Status: OPEN | |
| Kentucky | -115 |
| West Virginia | -115 |
| Wake Forest vs Cincinnati | |
| Type: Moneyline - Status: OPEN | |
| Wake Forest | -160 |
| Cincinnati | +120 |
| NC State vs Stetson | |
| Type: Moneyline - Status: OPEN | |
| NC State | -300 |
| Stetson | +215 |
| Louisville vs East Tennessee State | |
| Type: Moneyline - Status: OPEN | |
| Louisville | -125 |
| East Tennessee State | -105 |
| Texas (#2) vs Houston Christian | |
| Type: Moneyline - Status: OPEN | |
| Texas (#2) | -1300 |
| Houston Christian | +625 |
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| Type: Moneyline - Status: OPEN | |
| Arkansas (#3) | -5000 |
| North Dakota State | +1100 |
| Alabama vs Miami Florida | |
| Type: Moneyline - Status: OPEN | |
| Alabama | -160 |
| Miami Florida | +120 |
| TCU vs USC | |
| Type: Moneyline - Status: OPEN | |
| TCU | -200 |
| USC | +150 |
| Florida State (#9) vs Bethune Cookman | |
| Type: Moneyline - Status: OPEN | |
| Florida State (#9) | -900 |
| Bethune Cookman | +475 |
| LSU (#6) vs Arkansas Little Rock | |
| Type: Moneyline - Status: OPEN | |
| LSU (#6) | -4000 |
| Arkansas Little Rock | +1000 |
| Georgia Tech vs Western Kentucky | |
| Type: Moneyline - Status: OPEN | |
| Georgia Tech | -180 |
| Western Kentucky | +130 |
| Arizona vs Cal Poly | |
| Type: Moneyline - Status: OPEN | |
| Arizona | -115 |
| Cal Poly | -115 |
| UCLA (#15) vs Fresno State | |
| Type: Moneyline - Status: OPEN | |
| UCLA (#15) | -300 |
| Fresno State | +215 |
| Oklahoma vs Nebraska | |
| Type: Moneyline - Status: OPEN | |
| Oklahoma | -275 |
| Nebraska | +200 |
| Clemson (#11) vs USC Upstate | |
| Type: Moneyline - Status: OPEN | |
| Clemson (#11) | -360 |
| USC Upstate | +250 |
| Vanderbilt (#1) vs Wright State | |
| Type: Moneyline - Status: OPEN | |
| Vanderbilt (#1) | -650 |
| Wright State | +400 |
| Duke vs Oklahoma State | |
| Type: Moneyline - Status: OPEN | |
| Duke | -145 |
| Oklahoma State | +110 |
| Coastal Carolina (#13) vs Fairfield | |
| Type: Moneyline - Status: OPEN | |
| Coastal Carolina (#13) | -525 |
| Fairfield | +340 |
| Tennessee (#14) vs Miami Ohio | |
| Type: Moneyline - Status: OPEN | |
| Tennessee (#14) | -650 |
| Miami Ohio | +400 |
| Southern Mississippi (#16) vs Columbia | |
| Type: Moneyline - Status: OPEN | |
| Southern Mississippi (#16) | -500 |
| Columbia | +330 |
| Auburn (#4) vs Central Connecticut | |
| Type: Moneyline - Status: OPEN | |
| Auburn (#4) | -700 |
| Central Connecticut | +425 |
| Kansas State vs UTSA | |
| Type: Moneyline - Status: OPEN | |
| Kansas State | +105 |
| UTSA | -135 |
| Northeastern vs Mississippi State | |
| Type: Moneyline - Status: OPEN | |
| Northeastern | +115 |
| Mississippi State | -150 |
| Dallas Baptist vs Rhode Island | |
| Type: Moneyline - Status: OPEN | |
| Dallas Baptist | -320 |
| Rhode Island | +230 |
| Kansas vs Creighton | |
| Type: Moneyline - Status: OPEN | |
| Kansas | -180 |
| Creighton | +135 |
| Oregon State (#8) vs Saint Mary's CA | |
| Type: Moneyline - Status: OPEN | |
| Oregon State (#8) | -440 |
| Saint Mary’S Gaels | +295 |
| Mississippi (#10) vs Murray State | |
| Type: Moneyline - Status: OPEN | |
| Mississippi (#10) | -360 |
| Murray State | +250 |
| Oregon (#12) vs Utah Valley | |
| Type: Moneyline - Status: OPEN | |
| Oregon (#12) | -900 |
| Utah Valley | +475 |
| Arizona State vs UC Irvine | |
| Type: Moneyline - Status: OPEN | |
| Arizona State | -125 |
| UC Irvine | -105 |