New Blue Jays pitcher Edwin Jackson appeared in a game for his 14th major league team Wednesday, breaking a record that he had shared with Octavio Dotel.
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| Philadelphia Phillies vs Miami Marlins | |
| Type: Runline - Status: OPEN | |
| Miami Marlins - 1H | -120 |
| Philadelphia Phillies - 1H | -110 |
| Detroit Tigers vs Kansas City Royals | |
| Type: Moneyline - Status: OPEN | |
| Kansas City Royals - 1H | -105 |
| Detroit Tigers - 1H | -125 |
| Chicago Cubs vs Arizona Diamondbacks | |
| Type: Total - Status: OPEN | |
| Over - 1I | +250 |
| Under - 1I | -360 |
| Toronto Blue Jays vs Seattle Mariners | |
| Type: Total - Status: OPEN | |
| Over | -120 |
| Under | +100 |
| Texas Rangers vs Los Angeles Dodgers | |
| Type: Total - Status: OPEN | |
| Over - 1I | +240 |
| Under - 1I | -340 |
| Pittsburgh Pirates vs Cleveland Guardians | |
| Type: Moneyline - Status: OPEN | |
| Cleveland Guardians | +141 |
| Pittsburgh Pirates | -170 |
| New York Mets vs St. Louis Cardinals | |
| Type: Moneyline - Status: OPEN | |
| New York Mets - 1H | -180 |
| St. Louis Cardinals - 1H | +135 |
| Baltimore Orioles vs Cincinnati Reds | |
| Type: Runline - Status: OPEN | |
| Baltimore Orioles - 1H | -125 |
| Cincinnati Reds - 1H | -105 |
| Boston Red Sox vs Chicago White Sox | |
| Type: Moneyline - Status: OPEN | |
| Boston Red Sox - 1H | -300 |
| Chicago White Sox - 1H | +220 |
| Colorado Rockies vs Washington Nationals | |
| Type: Runline - Status: OPEN | |
| Washington Nationals | +115 |
| Colorado Rockies | -135 |
| Tampa Bay Rays vs New York Yankees | |
| Type: Runline - Status: OPEN | |
| Tampa Bay Rays - 1H | -120 |
| New York Yankees - 1H | -110 |
| Houston Astros vs San Diego Padres | |
| Type: Runline - Status: OPEN | |
| San Diego Padres | +130 |
| Houston Astros | -150 |
| Milwaukee Brewers vs Athletics | |
| Type: Moneyline - Status: OPEN | |
| Athletics - 1H | -105 |
| Milwaukee Brewers - 1H | -125 |
| Atlanta Braves vs Minnesota Twins | |
| Type: Runline - Status: OPEN | |
| Atlanta Braves - 1H | +100 |
| Minnesota Twins - 1H | -130 |
| Los Angeles Angels vs San Francisco Giants | |
| Type: Total - Status: OPEN | |
| Under | -105 |
| Over | -115 |