Veteran Kyle Higashioka, and not Gary Sanchez, will start Game 1 behind the plate when the New York Yankees face the Cleveland Indians.
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| Cleveland Guardians vs Milwaukee Brewers | |
| Type: Runline - Status: OPEN | |
| Cleveland Guardians - 1H | -125 |
| Milwaukee Brewers - 1H | -105 |
| Detroit Tigers vs Boston Red Sox | |
| Type: Runline - Status: OPEN | |
| Detroit Tigers - 1H | -150 |
| Boston Red Sox - 1H | +115 |
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| Type: Moneyline - Status: OPEN | |
| St. Louis Cardinals - 1I | +120 |
| Philadelphia Phillies - 1I | -160 |
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| Type: Runline - Status: OPEN | |
| New York Mets | +135 |
| Pittsburgh Pirates | -160 |
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| Type: Runline - Status: OPEN | |
| Atlanta Braves | +110 |
| Washington Nationals | -130 |
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| Type: Total - Status: OPEN | |
| Over | -110 |
| Under | -110 |
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| Type: Total - Status: OPEN | |
| Over - 1H | -125 |
| Under - 1H | -105 |
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| Type: Total - Status: OPEN | |
| Under | -105 |
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| Type: Runline - Status: OPEN | |
| San Diego Padres - 1H | +105 |
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| Type: Total - Status: OPEN | |
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| Samsung Lions | -130 |
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