One out away from having their wild-card lead trimmed to one-half game, the San Diego Padres bounced back for a big victory. Khalil Greene homered to left field with one out in the 10th inning to give the struggling Padres a desperately needed 5-4 win over the San Francisco Giants on Friday night. It was the third homer of the game for the Padres, who scored three runs in the last two innings.
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| Charros de Jalisco vs Tecolotes de los Dos Laredos | |
| Type: Total - Status: OPEN | |
| Under | -120 |
| Over | -120 |
| Guerreros de Oaxaca vs Tigres de Quintana Roo | |
| Type: Moneyline - Status: OPEN | |
| Guerreros de Oaxaca | -205 |
| Tigres de Quintana Roo | +145 |
| Conspiradores de Queretaro vs Pericos de Puebla | |
| Type: Moneyline - Status: OPEN | |
| Conspiradores de Queretaro | +110 |
| Pericos de Puebla | -155 |
| Generales De Durango vs Sultanes de Monterrey | |
| Type: Runline - Status: OPEN | |
| Generales De Durango | +100 |
| Sultanes de Monterrey | -140 |
| Cleveland Guardians vs Philadelphia Phillies | |
| Type: Moneyline - Status: OPEN | |
| Cleveland Guardians - 1I | +105 |
| Philadelphia Phillies - 1I | -135 |
| Rieleros de Aguascalientes vs Saraperos de Saltillo | |
| Type: Runline - Status: OPEN | |
| Rieleros de Aguascalientes | -150 |
| Saraperos de Saltillo | +105 |
| Olmecas de Tabasco vs Bravos de Leon | |
| Type: Runline - Status: OPEN | |
| Olmecas de Tabasco | +120 |
| Bravos de Leon | -170 |
| Leones de Yucatan vs El Aguila de Veracruz | |
| Type: Runline - Status: OPEN | |
| Leones de Yucatan | +140 |
| El Aguila de Veracruz | -200 |
| Algodoneros del Unión Laguna vs Toros de Tijuana | |
| Type: Moneyline - Status: OPEN | |
| Algodoneros del Unión Laguna | -125 |
| Toros de Tijuana | -115 |
| Detroit Tigers vs Boston Red Sox | |
| Type: Runline - Status: SUSPENDED | |
| Boston Red Sox - 1I | |
| Detroit Tigers - 1I | |
| New York Mets vs Pittsburgh Pirates | |
| Type: Runline - Status: OPEN | |
| New York Mets | +160 |
| Pittsburgh Pirates | -185 |
| Atlanta Braves vs Washington Nationals | |
| Type: Runline - Status: OPEN | |
| Atlanta Braves | +115 |
| Washington Nationals | -135 |
| Chicago Cubs vs Miami Marlins | |
| Type: Total - Status: SUSPENDED | |
| Over | |
| Under | |
| Texas Rangers vs Colorado Rockies | |
| Type: Total - Status: OPEN | |
| Over - 1H | -110 |
| Under - 1H | -120 |
| San Diego Padres vs Los Angeles Angels | |
| Type: Runline - Status: OPEN | |
| San Diego Padres - 1H | -135 |
| Los Angeles Angels - 1H | +105 |
| San Francisco Giants vs Arizona Diamondbacks | |
| Type: Runline - Status: OPEN | |
| Arizona Diamondbacks | -225 |
| San Francisco Giants | +185 |