Astros’ Michael Brantley drove in the first run of the game with 2nd-inning double to give the American League the early lead.
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| Fukuoka SoftBank Hawks vs Saitama Seibu Lions | |
| Type: Moneyline - Status: OPEN | |
| Fukuoka SoftBank Hawks | -130 |
| Saitama Seibu Lions | +100 |
| Chunichi Dragons vs Tokyo Yakult Swallows | |
| Type: Runline - Status: OPEN | |
| Chunichi Dragons | +225 |
| Tokyo Yakult Swallows | -310 |
| Hiroshima Toyo Carp vs Yomiuri Giants | |
| Type: Runline - Status: OPEN | |
| Hiroshima Toyo Carp | -185 |
| Yomiuri Giants | +140 |
| Hanwha Eagles vs Doosan Bears | |
| Type: Moneyline - Status: OPEN | |
| Hanwha Eagles | -105 |
| Doosan Bears | -125 |
| Kia Tigers vs Lotte Giants | |
| Type: Runline - Status: OPEN | |
| Kia Tigers | +135 |
| Lotte Giants | -175 |
| LG Twins vs Kiwoom Heroes | |
| Type: Moneyline - Status: OPEN | |
| LG Twins | -145 |
| Kiwoom Heroes | +110 |
| Samsung Lions vs KT Wiz | |
| Type: Moneyline - Status: OPEN | |
| Samsung Lions | -165 |
| KT Wiz | +125 |
| SSG Landers vs NC Dinos | |
| Type: Total - Status: OPEN | |
| Under | -110 |
| Over | -120 |
| Fubon Guardians vs TSG Hawks | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -115 |
| Wei Chuan Dragons vs CTBC Brothers | |
| Type: Moneyline - Status: OPEN | |
| Wei Chuan Dragons | -145 |
| CTBC Brothers | +110 |
| Rakuten Monkeys vs Uni-Lions | |
| Type: Moneyline - Status: OPEN | |
| Rakuten Monkeys | -145 |
| Uni-Lions | +110 |
| Baltimore Orioles vs Minnesota Twins | |
| Type: Runline - Status: OPEN | |
| Minnesota Twins | -200 |
| Baltimore Orioles | +170 |
| Philadelphia Phillies vs St. Louis Cardinals | |
| Type: Runline - Status: OPEN | |
| Philadelphia Phillies | +120 |
| St. Louis Cardinals | -140 |
| Cleveland Guardians vs Milwaukee Brewers | |
| Type: Total - Status: OPEN | |
| Over - 1H | -115 |
| Under - 1H | -115 |
| San Francisco Giants vs Arizona Diamondbacks | |
| Type: Moneyline - Status: OPEN | |
| Arizona Diamondbacks | -111 |
| San Francisco Giants | -109 |
| Seattle Mariners vs New York Yankees | |
| Type: Total - Status: OPEN | |
| Over - 1H | -115 |
| Under - 1H | -115 |
| Philadelphia Phillies vs St. Louis Cardinals | |
| Type: Moneyline - Status: OPEN | |
| Philadelphia Phillies | -149 |
| St. Louis Cardinals | +125 |
| Detroit Tigers vs Boston Red Sox | |
| Type: Total - Status: OPEN | |
| Under | +100 |
| Over | -120 |
| Toronto Blue Jays vs Tampa Bay Rays | |
| Type: Total - Status: OPEN | |
| Over - 1H | -105 |
| Under - 1H | -125 |
| New York Mets vs Pittsburgh Pirates | |
| Type: Moneyline - Status: OPEN | |
| Pittsburgh Pirates - 1H | +175 |
| New York Mets - 1H | -240 |
| Cincinnati Reds vs Chicago White Sox | |
| Type: Moneyline - Status: OPEN | |
| Cincinnati Reds | -225 |
| Chicago White Sox | +185 |
| Atlanta Braves vs Washington Nationals | |
| Type: Moneyline - Status: OPEN | |
| Atlanta Braves - 1I | -160 |
| Washington Nationals - 1I | +120 |
| Chicago Cubs vs Miami Marlins | |
| Type: Runline - Status: OPEN | |
| Chicago Cubs - 1H | -105 |
| Miami Marlins - 1H | -125 |
| Texas Rangers vs Colorado Rockies | |
| Type: Total - Status: OPEN | |
| Over | -105 |
| Under | -115 |
| Houston Astros vs Kansas City Royals | |
| Type: Moneyline - Status: OPEN | |
| Kansas City Royals | +115 |
| Houston Astros | -138 |
| San Diego Padres vs Los Angeles Angels | |
| Type: Total - Status: OPEN | |
| Under - 1H | -115 |
| Over - 1H | -115 |
| Los Angeles Dodgers vs Athletics | |
| Type: Total - Status: OPEN | |
| Under | -110 |
| Over | -110 |