The Brewers’ boom-or-bust offense exploded in the series opener — with the aid of four Cardinals’ errors, contributing to six unearned runs. For the Crew, Manny Pina homered, and Eric Thames, Travis Shaw and Jesus Aguilar all had multi-RBI games, while Matt Carpenter stayed hot with a homer for St. Louis. Brent Suter (7 IP, 2 ER) was terrific in outdueling Carlos Martinez, who only lasted four innings as his struggles continued.
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| Cleveland Guardians vs New York Yankees | |
| Type: Runline - Status: SUSPENDED | |
| New York Yankees - 1I | |
| Cleveland Guardians - 1I | |
| Detroit Tigers vs San Diego Padres | |
| Type: Runline - Status: OPEN | |
| Detroit Tigers | +195 |
| San Diego Padres | -235 |
| Miami Marlins vs Cincinnati Reds | |
| Type: Moneyline - Status: OPEN | |
| Miami Marlins - 1I | -115 |
| Cincinnati Reds - 1I | -115 |
| Boston Red Sox vs Seattle Mariners | |
| Type: Total - Status: OPEN | |
| Over | -110 |
| Under | -110 |
| Washington Nationals vs Baltimore Orioles | |
| Type: Total - Status: SUSPENDED | |
| Over - 1I | |
| Under - 1I | |
| New York Mets vs Philadelphia Phillies | |
| Type: Moneyline - Status: OPEN | |
| Philadelphia Phillies | -138 |
| New York Mets | +115 |
| Minnesota Twins vs Chicago White Sox | |
| Type: Total - Status: OPEN | |
| Over | -110 |
| Under | -110 |
| Chicago Cubs vs Los Angeles Dodgers | |
| Type: Moneyline - Status: OPEN | |
| Los Angeles Dodgers | -118 |
| Chicago Cubs | -102 |
| Kansas City Royals vs Colorado Rockies | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -105 |
| Houston Astros vs Toronto Blue Jays | |
| Type: Moneyline - Status: OPEN | |
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| Toronto Blue Jays - 1H | -120 |
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| San Francisco Giants - 1H | -145 |
| Milwaukee Brewers - 1H | +110 |
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| Type: Runline - Status: OPEN | |
| Athletics - 1H | -130 |
| Texas Rangers - 1H | +100 |
