Bartolo Colon passed Juan Marichal for the most wins by a Dominican-born pitcher, going six solid innings for his 244th victory in the series opener against the Royals. Shin-Soo Choo and Adrian Beltre backed the veteran right-hander with homers off Ian Kennedy, who gave up five runs to go with eight strikeouts. Beltre’s three-run jack was the 465th homer of his career, tying him with Dave Winfield and Miguel Cabrera for 34th all time.
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| Yokohama DeNa BayStars vs Hanshin Tigers | |
| Type: Moneyline - Status: OPEN | |
| Yokohama DeNa BayStars | -135 |
| Hanshin Tigers | +105 |
| Chiba Lotte Marines vs Saitama Seibu Lions | |
| Type: Moneyline - Status: OPEN | |
| Chiba Lotte Marines | -200 |
| Saitama Seibu Lions | +150 |
| Fukuoka SoftBank Hawks vs Orix Buffaloes | |
| Type: Runline - Status: OPEN | |
| Fukuoka SoftBank Hawks | +190 |
| Orix Buffaloes | -260 |
| Hokkaido Nippon-Ham Fighters vs Tohoku Rakuten Golden Eagles | |
| Type: Runline - Status: OPEN | |
| Hokkaido Nippon-Ham Fighters | +165 |
| Tohoku Rakuten Golden Eagles | -220 |
| Hiroshima Toyo Carp vs Tokyo Yakult Swallows | |
| Type: Moneyline - Status: OPEN | |
| Hiroshima Toyo Carp | -175 |
| Tokyo Yakult Swallows | +135 |
| Yomiuri Giants vs Chunichi Dragons | |
| Type: Runline - Status: OPEN | |
| Yomiuri Giants | +120 |
| Chunichi Dragons | -155 |
| Kiwoom Heroes vs Doosan Bears | |
| Type: Total - Status: OPEN | |
| Over | -115 |
| Under | -115 |
| KT Wiz vs SSG Landers | |
| Type: Total - Status: OPEN | |
| Under | -110 |
| Over | -120 |
| LG Twins vs NC Dinos | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -115 |
| Lotte Giants vs Hanwha Eagles | |
| Type: Moneyline - Status: OPEN | |
| Lotte Giants | -120 |
| Hanwha Eagles | -110 |
| Samsung Lions vs Kia Tigers | |
| Type: Moneyline - Status: OPEN | |
| Kia Tigers | +110 |
| Samsung Lions | -145 |
| Atlanta Braves vs St. Louis Cardinals | |
| Type: Moneyline - Status: OPEN | |
| St. Louis Cardinals - 1H | +125 |
| Atlanta Braves - 1H | -165 |
| Cleveland Guardians vs New York Yankees | |
| Type: Moneyline - Status: OPEN | |
| New York Yankees | -147 |
| Cleveland Guardians | +123 |
| Detroit Tigers vs San Diego Padres | |
| Type: Moneyline - Status: OPEN | |
| San Diego Padres - 1H | +130 |
| Detroit Tigers - 1H | -170 |
| Miami Marlins vs Cincinnati Reds | |
| Type: Runline - Status: OPEN | |
| Miami Marlins | +155 |
| Cincinnati Reds | -180 |
| New York Mets vs Philadelphia Phillies | |
| Type: Total - Status: SUSPENDED | |
| Over - 1I | |
| Under - 1I | |
| Boston Red Sox vs Seattle Mariners | |
| Type: Runline - Status: OPEN | |
| Seattle Mariners - 1H | -120 |
| Boston Red Sox - 1H | -110 |
| Washington Nationals vs Baltimore Orioles | |
| Type: Moneyline - Status: OPEN | |
| Washington Nationals - 1I | -110 |
| Baltimore Orioles - 1I | -120 |
| Kansas City Royals vs Colorado Rockies | |
| Type: Total - Status: OPEN | |
| Over - 1H | -125 |
| Under - 1H | -105 |
| Houston Astros vs Toronto Blue Jays | |
| Type: Runline - Status: OPEN | |
| Houston Astros - 1H | +115 |
| Toronto Blue Jays - 1H | -150 |
| Los Angeles Angels vs Pittsburgh Pirates | |
| Type: Moneyline - Status: OPEN | |
| Pittsburgh Pirates - 1H | +115 |
| Los Angeles Angels - 1H | -150 |
| Arizona Diamondbacks vs Tampa Bay Rays | |
| Type: Moneyline - Status: OPEN | |
| Tampa Bay Rays - 1I | +110 |
| Arizona Diamondbacks - 1I | -145 |
| San Francisco Giants vs Milwaukee Brewers | |
| Type: Total - Status: OPEN | |
| Under - 1H | -115 |
| Over - 1H | -115 |
| Athletics vs Texas Rangers | |
| Type: Total - Status: OPEN | |
| Under - 1H | -125 |
| Over - 1H | -105 |
