Milwaukee starter Jhoulys Chacin had retired the Cubs in order through three innings. Daniel Murphy led off the fourth with his 10th homer of the season and fourth since joining the Cubs. Then it got wild.
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| Shandong Blue Whale vs Guangdong Leopard | |
| Type: Total - Status: OPEN | |
| Under | -105 |
| Over | -125 |
| Cleveland Guardians vs Milwaukee Brewers | |
| Type: Runline - Status: OPEN | |
| Cleveland Guardians - 1H | -135 |
| Milwaukee Brewers - 1H | +105 |
| Detroit Tigers vs Boston Red Sox | |
| Type: Runline - Status: SUSPENDED | |
| Boston Red Sox - 1I | |
| Detroit Tigers - 1I | |
| New York Mets vs Pittsburgh Pirates | |
| Type: Runline - Status: OPEN | |
| New York Mets | +165 |
| Pittsburgh Pirates | -195 |
| Atlanta Braves vs Washington Nationals | |
| Type: Runline - Status: OPEN | |
| Atlanta Braves | +115 |
| Washington Nationals | -135 |
| Chicago Cubs vs Miami Marlins | |
| Type: Total - Status: SUSPENDED | |
| Over | |
| Under | |
| Texas Rangers vs Colorado Rockies | |
| Type: Total - Status: OPEN | |
| Over - 1H | -110 |
| Under - 1H | -120 |
| San Diego Padres vs Los Angeles Angels | |
| Type: Runline - Status: OPEN | |
| San Diego Padres - 1H | -135 |
| Los Angeles Angels - 1H | +105 |
| San Francisco Giants vs Arizona Diamondbacks | |
| Type: Runline - Status: OPEN | |
| Arizona Diamondbacks | -220 |
| San Francisco Giants | +180 |
