The Red Sox and the Astros, who combined to win 211 games in the regular season en route to posting the top two records in the Major Leagues, will square off in the American League Championship Series in what sets up to be a tantalizing best-of-seven series.
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| Algodoneros del Unión Laguna vs Sultanes de Monterrey | |
| Type: Moneyline - Status: OPEN | |
| Algodoneros del Unión Laguna | -115 |
| Sultanes de Monterrey | -125 |
| El Paso Chihuahuas vs Albuquerque Isotopes | |
| Type: Total - Status: OPEN | |
| Under | -110 |
| Over | -120 |
| Florida State (#9) vs Oregon State (#8) | |
| Type: Moneyline - Status: OPEN | |
| Florida State (#9) | -165 |
| Oregon State (#8) | +125 |
| Salt Lake Bees vs Round Rock Express | |
| Type: Moneyline - Status: OPEN | |
| Salt Lake Bees | +100 |
| Round Rock Express | -130 |
| Tacoma Rainiers vs Las Vegas Aviators | |
| Type: Runline - Status: OPEN | |
| Tacoma Rainiers | +170 |
| Las Vegas Aviators | -230 |
| Los Angeles Angels vs Seattle Mariners | |
| Type: Moneyline - Status: OPEN | |
| Los Angeles Angels - 1H | +135 |
| Seattle Mariners - 1H | -180 |
| Colorado Rockies vs New York Mets | |
| Type: Moneyline - Status: OPEN | |
| Colorado Rockies - 1H | +225 |
| New York Mets - 1H | -310 |
| Athletics vs Baltimore Orioles | |
| Type: Runline - Status: OPEN | |
| Athletics - 1H | -145 |
| Baltimore Orioles - 1H | +110 |
| Hiroshima Toyo Carp vs Saitama Seibu Lions | |
| Type: Runline - Status: OPEN | |
| Hiroshima Toyo Carp | -175 |
| Saitama Seibu Lions | +135 |
| Tokyo Yakult Swallows vs Fukuoka SoftBank Hawks | |
| Type: Moneyline - Status: OPEN | |
| Tokyo Yakult Swallows | +135 |
| Fukuoka SoftBank Hawks | -175 |
| Chunichi Dragons vs Chiba Lotte Marines | |
| Type: Moneyline - Status: OPEN | |
| Chunichi Dragons | -105 |
| Chiba Lotte Marines | -125 |
| Yokohama DeNa BayStars vs Hokkaido Nippon-Ham Fighters | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -115 |
| Hanshin Tigers vs Orix Buffaloes | |
| Type: Moneyline - Status: OPEN | |
| Hanshin Tigers | -165 |
| Orix Buffaloes | +125 |
| Yomiuri Giants vs Tohoku Rakuten Golden Eagles | |
| Type: Total - Status: OPEN | |
| Under | -110 |
| Over | -120 |
| Kiwoom Heroes vs LG Twins | |
| Type: Runline - Status: OPEN | |
| Kiwoom Heroes | +110 |
| LG Twins | -145 |
| Doosan Bears vs Lotte Giants | |
| Type: Total - Status: OPEN | |
| Under | -110 |
| Over | -120 |
| Kia Tigers vs Hanwha Eagles | |
| Type: Runline - Status: OPEN | |
| Kia Tigers | -145 |
| Hanwha Eagles | +110 |
| KT Wiz vs SSG Landers | |
| Type: Moneyline - Status: OPEN | |
| KT Wiz | -200 |
| SSG Landers | +150 |
| Samsung Lions vs NC Dinos | |
| Type: Runline - Status: OPEN | |
| Samsung Lions | -145 |
| NC Dinos | +110 |
| Wei Chuan Dragons vs Uni-Lions | |
| Type: Moneyline - Status: OPEN | |
| Wei Chuan Dragons | -105 |
| Uni-Lions | -125 |
| Fubon Guardians vs CTBC Brothers | |
| Type: Total - Status: OPEN | |
| Under | -165 |
| Over | +125 |
| Rakuten Monkeys vs TSG Hawks | |
| Type: Total - Status: OPEN | |
| Under | -125 |
| Over | -105 |
| Louisville vs Miami Florida | |
| Type: Moneyline - Status: OPEN | |
| Louisville | -180 |
| Miami Florida | +135 |
| North Carolina (#5) vs Arizona | |
| Type: Moneyline - Status: OPEN | |
| North Carolina (#5) | -330 |
| Arizona | +235 |
| Murray State vs Duke | |
| Type: Moneyline - Status: OPEN | |
| Murray State | +225 |
| Duke | -310 |
| Tennessee (#14) vs Arkansas (#3) | |
| Type: Moneyline - Status: OPEN | |
| Tennessee (#14) | -130 |
| Arkansas (#3) | +100 |
| West Virginia vs LSU (#6) | |
| Type: Runline - Status: OPEN | |
| West Virginia | -110 |
| LSU (#6) | -120 |