The Astros’ quest for a repeat World Series title got off to a fast start, as Houston rode four homers and a strong Justin Verlander start to a win over Cleveland in Game 1 of the American League Division Series. Verlander and Indians starter Corey Kluber traded hitless frames over the first three innings, but Alex Bregman broke through with a homer to lead off the fourth, and George Springer and Jose Altuve went deep back to back off the Tribe ace in the fifth. Verlander kept Cleveland out of the hit column until the sixth, when the Indians plated a pair and chased the starter. Martin Maldonado added Houston’s fourth homer as part of a two-run seventh inning.
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| Boston Red Sox vs Chicago White Sox | |
| Type: Total - Status: OPEN | |
| Over - 1H | -125 |
| Under - 1H | -105 |
| Cleveland Guardians vs New York Yankees | |
| Type: Moneyline - Status: OPEN | |
| New York Yankees - 1I | -105 |
| Cleveland Guardians - 1I | -125 |
| Miami Marlins vs Cincinnati Reds | |
| Type: Moneyline - Status: OPEN | |
| Miami Marlins - 1I | -115 |
| Cincinnati Reds - 1I | -115 |
| Detroit Tigers vs San Diego Padres | |
| Type: Moneyline - Status: OPEN | |
| Detroit Tigers - 1H | -165 |
| San Diego Padres - 1H | +125 |
| New York Mets vs Philadelphia Phillies | |
| Type: Total - Status: SUSPENDED | |
| Over - 1I | |
| Under - 1I | |
| Atlanta Braves vs St. Louis Cardinals | |
| Type: Total - Status: OPEN | |
| Over | -115 |
| Under | -105 |
| Houston Astros vs Toronto Blue Jays | |
| Type: Total - Status: OPEN | |
| Under | -120 |
| Over | +100 |
| San Francisco Giants vs Milwaukee Brewers | |
| Type: Runline - Status: OPEN | |
| San Francisco Giants - 1H | +100 |
| Milwaukee Brewers - 1H | -130 |
| Hiroshima Toyo Carp vs Tokyo Yakult Swallows | |
| Type: Total - Status: OPEN | |
| Under | -125 |
| Over | -105 |
| Kiwoom Heroes vs Doosan Bears | |
| Type: Moneyline - Status: OPEN | |
| Kiwoom Heroes | +100 |
| Doosan Bears | -130 |
| KT Wiz vs SSG Landers | |
| Type: Total - Status: OPEN | |
| Under | -120 |
| Over | -110 |
| LG Twins vs NC Dinos | |
| Type: Total - Status: OPEN | |
| Over | -115 |
| Under | -115 |
| Lotte Giants vs Hanwha Eagles | |
| Type: Runline - Status: OPEN | |
| Lotte Giants | +150 |
| Hanwha Eagles | -200 |
| Samsung Lions vs Kia Tigers | |
| Type: Runline - Status: OPEN | |
| Samsung Lions | +120 |
| Kia Tigers | -155 |