Confetti fell and euphoria reigned as manager Ozzie Guillen and his team paraded through the streets after the Chicago White Sox won the World Series for the first time in 88 years. That day less than two years ago seems so long ago now. In a stunning and swift collapse, the White Sox have plummeted to the bottom of the AL Central at 57-74.
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| Cleveland Guardians vs Milwaukee Brewers | |
| Type: Runline - Status: OPEN | |
| Cleveland Guardians - 1H | -125 |
| Milwaukee Brewers - 1H | -105 |
| Detroit Tigers vs Boston Red Sox | |
| Type: Runline - Status: SUSPENDED | |
| Boston Red Sox - 1I | |
| Detroit Tigers - 1I | |
| Philadelphia Phillies vs St. Louis Cardinals | |
| Type: Moneyline - Status: OPEN | |
| St. Louis Cardinals - 1I | +120 |
| Philadelphia Phillies - 1I | -160 |
| New York Mets vs Pittsburgh Pirates | |
| Type: Runline - Status: OPEN | |
| New York Mets | +155 |
| Pittsburgh Pirates | -180 |
| Atlanta Braves vs Washington Nationals | |
| Type: Runline - Status: OPEN | |
| Atlanta Braves | +120 |
| Washington Nationals | -140 |
| Chicago Cubs vs Miami Marlins | |
| Type: Total - Status: OPEN | |
| Over | -110 |
| Under | -110 |
| Texas Rangers vs Colorado Rockies | |
| Type: Total - Status: OPEN | |
| Over - 1H | -105 |
| Under - 1H | -125 |
| Houston Astros vs Kansas City Royals | |
| Type: Total - Status: OPEN | |
| Under | -120 |
| Over | +100 |
| San Diego Padres vs Los Angeles Angels | |
| Type: Runline - Status: OPEN | |
| San Diego Padres - 1H | +100 |
| Los Angeles Angels - 1H | -130 |
| Seattle Mariners vs New York Yankees | |
| Type: Moneyline - Status: OPEN | |
| Seattle Mariners - 1H | +105 |
| New York Yankees - 1H | -135 |
| San Francisco Giants vs Arizona Diamondbacks | |
| Type: Runline - Status: OPEN | |
| Arizona Diamondbacks | -220 |
| San Francisco Giants | +180 |