Despite another rash of injuries and an unseen challenge replay that went against them, the Niners persevered to put away a 36-24 victory over the Seahawks they badly needed.
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |