Hall of Famer Tony La Russa, who last managed in the major leagues by guiding the Cardinals to the World Series in 2011, has been hired by the White Sox at age 76.
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| Louisville vs Miami Florida | |
| Type: Moneyline - Status: OPEN | |
| Louisville | -190 |
| Miami Florida | +145 |
| North Carolina (#5) vs Arizona | |
| Type: Moneyline - Status: OPEN | |
| North Carolina (#5) | -330 |
| Arizona | +235 |
| Murray State vs Duke | |
| Type: Moneyline - Status: OPEN | |
| Murray State | +225 |
| Duke | -310 |
| Tampa Bay Rays vs Miami Marlins | |
| Type: Total - Status: OPEN | |
| Under - 1H | -120 |
| Over - 1H | -110 |
| Milwaukee Brewers vs San Diego Padres | |
| Type: Moneyline - Status: OPEN | |
| Milwaukee Brewers - 1H | -165 |
| San Diego Padres - 1H | +125 |
| Pittsburgh Pirates vs Philadelphia Phillies | |
| Type: Moneyline - Status: OPEN | |
| Pittsburgh Pirates - 1I | -130 |
| Philadelphia Phillies - 1I | +100 |
| Washington Nationals vs Texas Rangers | |
| Type: Total - Status: OPEN | |
| Under | -105 |
| Over | -115 |
| Cleveland Guardians vs Houston Astros | |
| Type: Total - Status: OPEN | |
| Under - 1H | -105 |
| Over - 1H | -125 |
| Detroit Tigers vs Chicago Cubs | |
| Type: Total - Status: OPEN | |
| Under - 1H | -120 |
| Over - 1H | -110 |
| Cincinnati Reds vs Arizona Diamondbacks | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -105 |
| Minnesota Twins vs Toronto Blue Jays | |
| Type: Total - Status: OPEN | |
| Under - 1H | -120 |
| Over - 1H | -110 |
| Chicago White Sox vs Kansas City Royals | |
| Type: Total - Status: OPEN | |
| Under | -120 |
| Over | +100 |
| St. Louis Cardinals vs Los Angeles Dodgers | |
| Type: Moneyline - Status: OPEN | |
| St. Louis Cardinals - 1I | -115 |
| Los Angeles Dodgers - 1I | -115 |
| Tennessee (#14) vs Arkansas (#3) | |
| Type: Moneyline - Status: OPEN | |
| Tennessee (#14) | -130 |
| Arkansas (#3) | +100 |
| UTSA vs UCLA (#15) | |
| Type: Total - Status: OPEN | |
| Under | -110 |
| Over | -120 |
| Colorado Rockies vs New York Mets | |
| Type: Moneyline - Status: OPEN | |
| Colorado Rockies - 1I | +145 |
| New York Mets - 1I | -190 |
| San Francisco Giants vs Atlanta Braves | |
| Type: Runline - Status: SUSPENDED | |
| San Francisco Giants - 1I | |
| Atlanta Braves - 1I | |
| Los Angeles Angels vs Seattle Mariners | |
| Type: Moneyline - Status: OPEN | |
| Los Angeles Angels - 1I | -110 |
| Seattle Mariners - 1I | -120 |
| West Virginia vs LSU (#6) | |
| Type: Runline - Status: OPEN | |
| West Virginia | -110 |
| LSU (#6) | -120 |
| New York Yankees vs Boston Red Sox | |
| Type: Moneyline - Status: OPEN | |
| New York Yankees - 1I | -180 |
| Boston Red Sox - 1I | +135 |
| Oregon State (#8) vs Florida State (#9) | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -115 |
