Eli Manning will try to resurrect his NFL career in the stadium where he made his debut 15 years ago. The two-time Super Bowl MVP makes his first start since Week 2 when the New York Giants (2-10) visit the Philadelphia Eagles (5-7) on Monday night. Manning is filling in for injured rookie Daniel Jones
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| Detroit Lions vs Los Angeles Chargers | |
| Type: Point Spread - Status: OPEN | |
| Detroit Lions | -105 |
| Los Angeles Chargers | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |
