Coach Kyle Shanahan gathered his team during the offseason program and delivered a clear message. After one year of rebuilding and one plagued by injuries, the San Francisco 49ers had no more excuses. The third year of the Shanahan-John Lynch era was time for the struggling franchise to take a big
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |
