As part of the celebration of its 100th season, the NFL will break from tradition and feature the Packers vs. the Bears in its season opener Sept. 5. Usually, the Super Bowl champion is the home team for the prime-time opener, but the league wants to salute historic rivalries in 2019. The teams have
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |
