In 2018, Shohei Ohtani and Ronald Acuna Jr. entered the season as Rookie of the Year contenders, if not front-runners, in each league. But sometimes Rookies of the Year come on unexpectedly. With that in mind, here is a potential ROY candidate from each organization.
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| Shandong Blue Whale vs Guangdong Leopard | |
| Type: Total - Status: OPEN | |
| Under | -105 |
| Over | -125 |
| Cleveland Guardians vs Milwaukee Brewers | |
| Type: Runline - Status: OPEN | |
| Cleveland Guardians - 1H | -135 |
| Milwaukee Brewers - 1H | +105 |
| Detroit Tigers vs Boston Red Sox | |
| Type: Runline - Status: SUSPENDED | |
| Boston Red Sox - 1I | |
| Detroit Tigers - 1I | |
| New York Mets vs Pittsburgh Pirates | |
| Type: Runline - Status: OPEN | |
| New York Mets | +165 |
| Pittsburgh Pirates | -195 |
| Atlanta Braves vs Washington Nationals | |
| Type: Runline - Status: OPEN | |
| Atlanta Braves | +115 |
| Washington Nationals | -135 |
| Chicago Cubs vs Miami Marlins | |
| Type: Total - Status: SUSPENDED | |
| Over | |
| Under | |
| Texas Rangers vs Colorado Rockies | |
| Type: Total - Status: OPEN | |
| Over - 1H | -110 |
| Under - 1H | -120 |
| San Diego Padres vs Los Angeles Angels | |
| Type: Runline - Status: OPEN | |
| San Diego Padres - 1H | -135 |
| Los Angeles Angels - 1H | +105 |
| San Francisco Giants vs Arizona Diamondbacks | |
| Type: Runline - Status: OPEN | |
| Arizona Diamondbacks | -220 |
| San Francisco Giants | +180 |