It’s not often that the two best teams in the Major Leagues — going by regular season record — meet in the postseason with a league pennant on the line. In 1969, baseball began to expand and split each league into two divisions, creating a need for the American League and National League Championship Series. Since then, the clubs with the two best records in MLB have met in the ALCS or NLCS just eight times.
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| Albuquerque Isotopes vs Tacoma Rainiers | |
| Type: Moneyline - Status: OPEN | |
| Albuquerque Isotopes | -120 |
| Tacoma Rainiers | -110 |
| Conspiradores de Queretaro vs Tigres de Quintana Roo | |
| Type: Moneyline - Status: OPEN | |
| Conspiradores de Queretaro | -140 |
| Tigres de Quintana Roo | +100 |
| Pericos de Puebla vs Leones de Yucatan | |
| Type: Moneyline - Status: OPEN | |
| Pericos de Puebla | -215 |
| Leones de Yucatan | +150 |
| Sultanes de Monterrey vs Dorados de Chihuahua | |
| Type: Runline - Status: OPEN | |
| Sultanes de Monterrey | -160 |
| Dorados de Chihuahua | +115 |
| Piratas de Campeche vs El Aguila de Veracruz | |
| Type: Total - Status: OPEN | |
| Under | -120 |
| Over | -120 |
| Algodoneros del Unión Laguna vs Rieleros de Aguascalientes | |
| Type: Total - Status: OPEN | |
| Under | -120 |
| Over | -120 |
| Bravos de Leon vs Guerreros de Oaxaca | |
| Type: Total - Status: OPEN | |
| Under | -130 |
| Over | -110 |
| Saraperos de Saltillo vs Tecolotes de los Dos Laredos | |
| Type: Total - Status: OPEN | |
| Under | -120 |
| Over | -120 |
| Las Vegas Aviators vs El Paso Chihuahuas | |
| Type: Moneyline - Status: OPEN | |
| Las Vegas Aviators | -150 |
| El Paso Chihuahuas | +115 |
| Generales De Durango vs Charros de Jalisco | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -125 |
| San Diego Padres vs Los Angeles Angels | |
| Type: Total - Status: OPEN | |
| Over - 1I | +210 |
| Under - 1I | -290 |
| Sacramento River Cats vs Salt Lake Bees | |
| Type: Moneyline - Status: OPEN | |
| Sacramento River Cats | -150 |
| Salt Lake Bees | +115 |
| Acereros de Monclova vs Toros de Tijuana | |
| Type: Runline - Status: OPEN | |
| Acereros de Monclova | -170 |
| Toros de Tijuana | +120 |
| Los Angeles Dodgers vs Athletics | |
| Type: Total - Status: OPEN | |
| Under | +100 |
| Over | -120 |
| Hokkaido Nippon-Ham Fighters vs Orix Buffaloes | |
| Type: Moneyline - Status: OPEN | |
| Hokkaido Nippon-Ham Fighters | -115 |
| Orix Buffaloes | -115 |
| Fukuoka SoftBank Hawks vs Saitama Seibu Lions | |
| Type: Runline - Status: OPEN | |
| Fukuoka SoftBank Hawks | +150 |
| Saitama Seibu Lions | -200 |
| Tohoku Rakuten Golden Eagles vs Chiba Lotte Marines | |
| Type: Runline - Status: OPEN | |
| Tohoku Rakuten Golden Eagles | +180 |
| Chiba Lotte Marines | -240 |
| Hiroshima Toyo Carp vs Yomiuri Giants | |
| Type: Moneyline - Status: OPEN | |
| Hiroshima Toyo Carp | +120 |
| Yomiuri Giants | -155 |
| Yokohama DeNa BayStars vs Hanshin Tigers | |
| Type: Total - Status: OPEN | |
| Under | -105 |
| Over | -125 |
| Hanwha Eagles vs Doosan Bears | |
| Type: Moneyline - Status: OPEN | |
| Hanwha Eagles | -125 |
| Doosan Bears | -105 |
| Kia Tigers vs Lotte Giants | |
| Type: Moneyline - Status: OPEN | |
| Kia Tigers | -185 |
| Lotte Giants | +140 |
| LG Twins vs Kiwoom Heroes | |
| Type: Moneyline - Status: OPEN | |
| LG Twins | -325 |
| Kiwoom Heroes | +230 |
| Samsung Lions vs KT Wiz | |
| Type: Total - Status: OPEN | |
| Under | -105 |
| Over | -125 |
| SSG Landers vs NC Dinos | |
| Type: Runline - Status: OPEN | |
| SSG Landers | +155 |
| NC Dinos | -205 |
| Rakuten Monkeys vs Uni-Lions | |
| Type: Runline - Status: OPEN | |
| Rakuten Monkeys | -150 |
| Uni-Lions | +115 |
| Atlanta Braves vs Washington Nationals | |
| Type: Moneyline - Status: OPEN | |
| Washington Nationals | +175 |
| Atlanta Braves | -215 |
| Baltimore Orioles vs Minnesota Twins | |
| Type: Total - Status: OPEN | |
| Under - 1H | -125 |
| Over - 1H | -105 |
| Cincinnati Reds vs Chicago White Sox | |
| Type: Runline - Status: OPEN | |
| Cincinnati Reds - 1H | -110 |
| Chicago White Sox - 1H | -120 |
| Toronto Blue Jays vs Tampa Bay Rays | |
| Type: Moneyline - Status: OPEN | |
| Tampa Bay Rays - 1I | +120 |
| Toronto Blue Jays - 1I | -160 |