Led by Reggie Bush, the Lions ran wild against the Packers on Thanksgiving in 2013. It is the last time Detroit produced a 100-yard rusher.
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |