Week 1 of the 2018 NFL regular season will start Thursday with Eagles vs. Falcons, and everybody from Average Joes to professional bettors are already making their picks. NFL odds are shifting dramatically as sportsbooks take plenty of action on a full slate of 16 games. The defending champion Philadelphia
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |