Los Angeles Angels manager Mike Scioscia will reportedly step down following the the 2018 season, which will be his 19th with the team.
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| Tohoku Rakuten Golden Eagles vs Fukuoka SoftBank Hawks | |
| Type: Total - Status: OPEN | |
| Under | -105 |
| Over | -125 |
| Hokkaido Nippon-Ham Fighters vs Chiba Lotte Marines | |
| Type: Total - Status: OPEN | |
| Under | -110 |
| Over | -120 |
| Chunichi Dragons vs Yomiuri Giants | |
| Type: Runline - Status: OPEN | |
| Chunichi Dragons | -220 |
| Yomiuri Giants | +165 |
| Hiroshima Toyo Carp vs Hanshin Tigers | |
| Type: Runline - Status: OPEN | |
| Hiroshima Toyo Carp | -190 |
| Hanshin Tigers | +145 |
| Yokohama DeNa BayStars vs Tokyo Yakult Swallows | |
| Type: Total - Status: OPEN | |
| Under | +100 |
| Over | -130 |
| Kiwoom Heroes vs Doosan Bears | |
| Type: Runline - Status: OPEN | |
| Kiwoom Heroes | +160 |
| Doosan Bears | -210 |
| Shandong Blue Whale vs Jiangsu Horse | |
| Type: Total - Status: OPEN | |
| Under | +100 |
| Over | -130 |
| Orix Buffaloes vs Saitama Seibu Lions | |
| Type: Total - Status: OPEN | |
| Under | -115 |
| Over | -115 |
| KT Wiz vs Kia Tigers | |
| Type: Runline - Status: OPEN | |
| KT Wiz | -165 |
| Kia Tigers | +125 |
| LG Twins vs Samsung Lions | |
| Type: Runline - Status: OPEN | |
| LG Twins | +185 |
| Samsung Lions | -250 |
| Lotte Giants vs SSG Landers | |
| Type: Moneyline - Status: OPEN | |
| Lotte Giants | +125 |
| SSG Landers | -165 |
| NC Dinos vs Hanwha Eagles | |
| Type: Total - Status: OPEN | |
| Under | -120 |
| Over | -110 |
| TSG Hawks vs Fubon Guardians | |
| Type: Total - Status: OPEN | |
| Under | -125 |
| Over | -105 |
| Uni-Lions vs Rakuten Monkeys | |
| Type: Total - Status: OPEN | |
| Under | -130 |
| Over | +100 |
| CTBC Brothers vs Wei Chuan Dragons | |
| Type: Moneyline - Status: OPEN | |
| CTBC Brothers | +100 |
| Wei Chuan Dragons | -130 |
| Texas Rangers vs St. Louis Cardinals | |
| Type: Moneyline - Status: OPEN | |
| Texas Rangers | -177 |
| St. Louis Cardinals | +145 |
| Baltimore Orioles vs Chicago White Sox | |
| Type: Total - Status: OPEN | |
| Under - 1H | -120 |
| Over - 1H | -110 |
| Philadelphia Phillies vs Milwaukee Brewers | |
| Type: Moneyline - Status: OPEN | |
| Philadelphia Phillies | -178 |
| Milwaukee Brewers | +146 |
| Atlanta Braves vs Boston Red Sox | |
| Type: Runline - Status: OPEN | |
| Atlanta Braves | -140 |
| Boston Red Sox | +120 |
| Toronto Blue Jays vs Athletics | |
| Type: Total - Status: OPEN | |
| Under | -105 |
| Over | -115 |
| Miami Marlins vs San Francisco Giants | |
| Type: Total - Status: OPEN | |
| Under - 1H | -115 |
| Over - 1H | -115 |
| Cleveland Guardians vs Los Angeles Angels | |
| Type: Runline - Status: OPEN | |
| Cleveland Guardians - 1H | -115 |
| Los Angeles Angels - 1H | -115 |
| New York Mets vs Colorado Rockies | |
| Type: Total - Status: OPEN | |
| Under - 1H | -105 |
| Over - 1H | -125 |
| Houston Astros vs Tampa Bay Rays | |
| Type: Moneyline - Status: OPEN | |
| Houston Astros - 1I | -170 |
| Tampa Bay Rays - 1I | +130 |
| Kansas City Royals vs Detroit Tigers | |
| Type: Total - Status: OPEN | |
| Under | -120 |
| Over | +100 |
| Chicago Cubs vs Cincinnati Reds | |
| Type: Runline - Status: SUSPENDED | |
| Chicago Cubs | |
| Cincinnati Reds | |
| Arizona Diamondbacks vs Washington Nationals | |
| Type: Runline - Status: OPEN | |
| Arizona Diamondbacks | -115 |
| Washington Nationals | -105 |
| Seattle Mariners vs Minnesota Twins | |
| Type: Moneyline - Status: OPEN | |
| Seattle Mariners - 1I | -135 |
| Minnesota Twins - 1I | +105 |
| San Diego Padres vs Pittsburgh Pirates | |
| Type: Moneyline - Status: OPEN | |
| San Diego Padres - 1I | -145 |
| Pittsburgh Pirates - 1I | +110 |
| Los Angeles Dodgers vs New York Yankees | |
| Type: Runline - Status: OPEN | |
| Los Angeles Dodgers | +120 |
| New York Yankees | -140 |