Indianapolis Colts quarterback Jacoby Brissett (7) is sacked by Tennessee Titans defensive end Karl Klug (97) and Derrick Morgan (91) in the first half of their game at Lucas Oil Stadium Sunday, Nov. 26, 2017. Matt Kryger/IndyStar
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| Detroit Lions vs Los Angeles Chargers | |
| Type: Point Spread - Status: OPEN | |
| Detroit Lions | -105 |
| Los Angeles Chargers | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |