For the fourth consecutive game in the National League Championship Series presented by Camping World, the Cubs took the lead on Wednesday, clubbing two homers off Dodgers lefty Alex Wood in the second inning — including the longest Statcast™ has tracked in the last three years of postseason play.
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| Atlanta Braves vs St. Louis Cardinals | |
| Type: Moneyline - Status: OPEN | |
| St. Louis Cardinals - 1H | +130 |
| Atlanta Braves - 1H | -170 |
| Cleveland Guardians vs New York Yankees | |
| Type: Moneyline - Status: OPEN | |
| New York Yankees | -160 |
| Cleveland Guardians | +134 |
| Detroit Tigers vs San Diego Padres | |
| Type: Moneyline - Status: OPEN | |
| San Diego Padres - 1H | +125 |
| Detroit Tigers - 1H | -165 |
| Miami Marlins vs Cincinnati Reds | |
| Type: Runline - Status: OPEN | |
| Miami Marlins | +170 |
| Cincinnati Reds | -200 |
| New York Mets vs Philadelphia Phillies | |
| Type: Total - Status: OPEN | |
| Over - 1I | +250 |
| Under - 1I | -360 |
| Boston Red Sox vs Seattle Mariners | |
| Type: Runline - Status: OPEN | |
| Seattle Mariners - 1H | -115 |
| Boston Red Sox - 1H | -115 |
| Washington Nationals vs Baltimore Orioles | |
| Type: Moneyline - Status: OPEN | |
| Washington Nationals - 1I | -110 |
| Baltimore Orioles - 1I | -120 |
| Chicago Cubs vs Los Angeles Dodgers | |
| Type: Total - Status: OPEN | |
| Over | -115 |
| Under | -105 |
| Minnesota Twins vs Chicago White Sox | |
| Type: Moneyline - Status: OPEN | |
| Chicago White Sox | +210 |
| Minnesota Twins | -260 |
| Kansas City Royals vs Colorado Rockies | |
| Type: Total - Status: OPEN | |
| Over - 1H | -120 |
| Under - 1H | -110 |
| Houston Astros vs Toronto Blue Jays | |
| Type: Runline - Status: OPEN | |
| Houston Astros - 1H | +110 |
| Toronto Blue Jays - 1H | -145 |
| Los Angeles Angels vs Pittsburgh Pirates | |
| Type: Moneyline - Status: OPEN | |
| Pittsburgh Pirates - 1H | +110 |
| Los Angeles Angels - 1H | -145 |
| Arizona Diamondbacks vs Tampa Bay Rays | |
| Type: Moneyline - Status: OPEN | |
| Tampa Bay Rays - 1I | +110 |
| Arizona Diamondbacks - 1I | -145 |
| San Francisco Giants vs Milwaukee Brewers | |
| Type: Total - Status: OPEN | |
| Under - 1H | -125 |
| Over - 1H | -105 |
| Athletics vs Texas Rangers | |
| Type: Total - Status: OPEN | |
| Under - 1H | -105 |
| Over - 1H | -125 |