The last time the Indianapolis Colts visited for the final preseason game, their starters could have driven over in a minivan and had plenty of room left for all their equipment. Their return trip could be just as meager. Two years ago, the Colts played only two starters — both on defense — in the final preseason game in Cincinnati.
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| Philadelphia Eagles vs Washington Commanders | |
| Type: Moneyline - Status: OPEN | |
| Washington Commanders - 2Q | +135 |
| Philadelphia Eagles - 2Q | -180 |
| Kansas City Chiefs vs Buffalo Bills | |
| Type: Moneyline - Status: OPEN | |
| Kansas City Chiefs - 1H | -120 |
| Buffalo Bills - 1H | +100 |
| NFC Conference vs AFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -145 |
| NFC Conference | +120 |
